Ingredient Dictionary

MALONIC ACID

Malonic acid is an alpha,-dicarboxylic acid in which the two carboxy groups are separated by a single methylene group.

Definition

Malonic acid is an alpha,-dicarboxylic acid in which the two carboxy groups are separated by a single methylene group. It has a role as a human metabolite. It is a conjugate acid of a malonate(1-).

Source: PubChem

US FDA substance register · UNII 9KX7ZMG0MK · registered name Malonic Acid · single chemical substance

Source: US FDA Unique Ingredient Identifier (UNII)

Cosmetic roles

Keeps pH steadyBUFFERING

Safety & regulatory references

Not classified under Korea’s toxic-substance GHS list · existing chemical substance

Source: Korea toxic substances GHS register (NIER)

Other restriction: ban substances that deplete the ozone layer

Source: EU CosIng ingredient list

Reviewed by CIR: Final Report of the Cosmetic Ingredient Review Expert Panel on the Safety Assessment of Dicarboxylic Acids, Salts and Esters

Source: US Cosmetic Ingredient Review (CIR)

More data — names, identifiers, properties, test records, literature

Official labels & definitions

JCIA labelling name マロン酸: 本品は、次の化学式で表される有機化合物である。

Source: JCIA labelling names (Japan)

Names & identifiers

MALONIC ACIDINCI말로닉애씨드Korean label name (MFDS standard)Propanedioic acidSynonymマロン酸Japanese labelling name

CAS No.chemical registry number: 141-82-2
EC No.EU chemical inventory number: 205-503-0
DTXSIDUS EPA chemical ID: DTXSID7021659
DTXCIDUS EPA compound ID: DTXCID401659

IUPAC: Propanedioic acid
Molecular formula: C3H4O4
Molecular weight: 104.061 g/mol

Measured properties

Appearance: solid
Colour: white
Flammability (solid, gas): combustible
Vapour pressure: 0.0015 ㎜Hg (@ 25 ℃)
Water solubility: 763000 ㎎/ℓ (@ 25 ℃)
Vapour density: 3.59
n-Octanol/water partition coefficient (Kow): -0.81
Decomposition temperature: 135 ℃
Molecular weight: 104.06

Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.

Source: KOSHA safety data sheets (Korea)

What products actually use it for

What the 4 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.

pH regulating agent1
Flavouring and nutrient1
Processing aids not otherwise specified1
Chelating agent1

Source: US EPA CompTox dashboard

Irritation and sensitisation studies

3 skin studies and 3 eye studies are on record.

Classed as moderate1

The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.

See all 6 studies

Classification not possible
Skin Irritation · Screening
Moderate or Mild Irritation
skin irritation: in vivo · Screening · other guideline: DOT (Transport-Classification) Guideliens according to
Classification not possible
Skin Sensitization · Screening
Category 6.4A (Category 2A)
Eye Irritation · Read Across
Serious eye damage/eye irritation - Category 1
Eye Irritation · Screening
Classification not possible
Eye Irritation · Screening