Definition
Alpha-mangostin is a member of the class of xanthones that is 9H-xanthene substituted by hydroxy group at positions 1, 3 and 6, a methoxy group at position 7, an oxo group at position 9 and prenyl groups at positions 2 and 8. Isolated from the stems of Cratoxylum cochinchinense, it exhibits antioxidant, antimicrobial and antitumour activities. It has a role as an antioxidant, an antimicrobial agent, an antineoplastic agent and a plant metabolite. It is a member of phenols, an aromatic ether and a member of xanthones.
Source: PubChem
US FDA substance register · UNII U6RIV93RU1 · registered name MANGOSTIN · single chemical substance
Cosmetic roles
More data — names, identifiers, properties, test records, literature
Official labels & definitions
JCIA labelling name マンゴスチン: 本品は、次の化学式で表される有機化合物である。
Source: JCIA labelling names (Japan)
Names & identifiers
- CAS No.chemical registry number
- 6147-11-1
- DTXSIDUS EPA chemical ID
- DTXSID00210420
- DTXCIDUS EPA compound ID
- DTXCID00132911
- IUPAC
- 1,3,6-Trihydroxy-7-methoxy-2,8-bis(3-methylbut-2-en-1-yl)-9H-xanthen-9-one
- Molecular formula
- C24H26O6
- Molecular weight
- 410.466 g/mol
Measured properties
- Appearance
- Solid · Faint yellow to yellow powder
- Melting point
- 180 - 181 °C
- Solubility
- Soluble in methanol
- Stability
- Stable under normal temperatures and pressures.
Values measured on the substance itself, not a specification for a commercial raw material.
Source: PubChem
What products actually use it for
What the 1 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Softener and conditioner1
Source: US EPA CompTox dashboard
Related literature
- α-Mangostin, a safe and natural product as a candidate skin-whitening agent · 2025
- Characteristics and Bioactivities of Carrageenan/Chitosan Microparticles Loading α-Mangostin · 2021
- Water-dispersible unadulterated α-mangostin particles for biomedical applications · 2020
- Characterization and Evaluation of ?-Mangostin-loaded Film-forming Gels for Acne Treatment · 2020
- In Vitro Permeation and Skin Retention of α-Mangostin Proniosome. · 2016
Linked databases 15
- ChEBI
- ChEMBL
- EU CosIng ingredient list 2
- JCIA labelling names (Japan)
- Korea Cosmetic Association ingredient dictionary
- MFDS (Korea) cosmetic ingredient register 2
- PubChem 2
- Tlooto literature search 2 3 4 5
- UniChem cross-reference IDs
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata
- Wikipedia · English · Chinese