D-mannitol is the D-enantiomer of mannitol.
How much products actually contain
No product states its amount yet.
Of the products containing it, 136 list it before the 1% line and 189 after it (usually 1% or less).
Products using this ingredient
12 of 322 confirmed · likeliest to carry enough first · See all 322
HanyulRed Rice Essence 150ml
FINDIVEBakuchiol Enzyme Powder Vitamin C Cleanser
HanyulHanyul Red Rice Moisture Firming Essence
Not Your Mother'sNot Your Mother's Dark Hair Dry Shampoo Powder
innisfreeGreen Tea Ceramide Milk Essence 160ml
DermafirmSoothing Repair Toning Cream
CCLIME BEAUTYCore Set Lift Bounce Ampoule
K18K18 AirWash™ dry shampoo 4oz
K18K18 Mini AirWash™ dry shampoo
BIODERMAAtoderm Intensive Gel Cream 500ml
Not Your Mother'sNot Your Mother's Advanced Dry Shampoo
AESTURARejuderm 365 Pore Elasticity Capsule Serum
Definition
D-mannitol is the D-enantiomer of mannitol. It has a role as a member of compatible osmolytes, a metabolite, an antiglaucoma drug, an osmotic diuretic, a sweetening agent, an allergen, a hapten, an Escherichia coli metabolite, a food anticaking agent, a food stabiliser, a food humectant, a food thickening agent and a food bulking agent.
Source: PubChem
Cosmetic roles
Safety & regulatory references
Not classified under Korea’s toxic-substance GHS list · existing chemical substance
Other restriction: ban substances that deplete the ozone layer
Source: EU CosIng ingredient list
Reviewed by CIR: Safety Assessment of Mannitol, Sorbitol and Xylitol as Used in Cosmetics
More data — names, identifiers, properties, test records, literature
Official labels & definitions
JCIA labelling name マンニトール: 本品は、次の化学式で表される糖アルコールである。
Source: JCIA labelling names (Japan)
Names & identifiers
- CAS No.chemical registry number
- 69-65-8
- CAS No.chemical registry number
- 87-78-5
- EC No.EU chemical inventory number
- 200-711-8
- EC No.EU chemical inventory number
- 201-770-2
- DTXSIDUS EPA chemical ID
- DTXSID1023235
- DTXCIDUS EPA compound ID
- DTXCID603235
- IUPAC
- D-Mannitol
- Molecular formula
- C6H14O6
- Molecular weight
- 182.172 g/mol
Measured properties
- Appearance
- D-mannitol appears as odorless white crystalline powder or free-flowing granules. Sweet taste. (NTP, 1992) · Dry Powder
- Odour
- Odorless · odourless
- Boiling point
- 563 °F at 3.5 mmHg (NTP, 1992) · 290-295 °C at 3.50E+00 mm Hg
- Melting point
- 331 to 334 °F (NTP, 1992) · 168 °C
- Solubility
- greater than or equal to 100 mg/mL at 68 °F (NTP, 1992) · 216000 mg/L (at 25 °C)
- Density
- 1.489 at 68 °F (NTP, 1992) - Denser than water, will sink · 1.52 @ 20 °C
- Stability
- Mannitol 25% (Invenex) was chemically and physically stable after five autoclavings at 250 °F for 15 min.
- Dissociation constant
- 13.5 (at 25 °C) · pKa = 13.50 @ 18 °C
- Colour
- white
- Melting/freezing point
- 166~168 ℃
- Initial boiling point and range
- 290~295 ℃ (at 3.5 mmHg)
- Vapour pressure
- 0.00000000492 ㎜Hg (@ 25 ℃, est.)
- Water solubility
- 216000 ㎎/ℓ (at 25 ℃)
- Vapour density
- 6.29
- Relative density
- 1.52 (at 20 ℃)
- n-Octanol/water partition coefficient (Kow)
- -3.10
- Molecular weight
- 182.17
Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.
Source: PubChem · KOSHA safety data sheets (Korea)
What products actually use it for
What the 14 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Flavouring and nutrient3
- Processing aids not otherwise specified2
- Humectant2
- Solvent1
- Lubricating agent1
- Softener and conditioner1
- Deodorizer1
- Binder1
2 other uses
- Anti-caking agent1
- Fragrance1
Source: US EPA CompTox dashboard
Related literature
- ROLE OF MANNITOL IN INDUCING DIRECT SOMATIC EMBRYOGENSIS OF DATE PALM · 2006
- Is the usage of mannitol mandatory in awake craniotomy? A comparative study · 2011
- The Cough Response to Inhaled Mannitol in Healthy Subjects · 2024
- Safety Assessment of Mannitol, Sorbitol, and Xylitol as Used in Cosmetics · 2019
- Topical Mannitol Reduces Inflammatory Edema in a Rat Model of Arthritis · 2012
Linked databases 20
- Australian Industrial Chemicals Inventory (AICIS)
- ChEBI
- China inventory of existing ingredients (IECIC)
- EU CosIng ingredient list 2
- JCIA labelling names (Japan)
- Korea Cosmetic Association ingredient dictionary
- Korea toxic substances GHS register (NIER)
- KOSHA safety data sheets (Korea)
- MFDS (Korea) cosmetic ingredient register 2
- NIST Chemistry WebBook
- PubChem 2
- Tlooto literature search 2 3 4 5
- UniChem cross-reference IDs
- US Cosmetic Ingredient Review (CIR) 2
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US National Toxicology Program reports
- Wikidata
- Wikipedia · Korean · English · Japanese · Chinese