Maslinic acid is a pentacyclic triterpenoid that is olean-12-ene substituted by hydroxy groups at positions 2 and 3 and a carboxy group at position 28 (the 2alpha,3beta stereoisomer).
Definition
Maslinic acid is a pentacyclic triterpenoid that is olean-12-ene substituted by hydroxy groups at positions 2 and 3 and a carboxy group at position 28 (the 2alpha,3beta stereoisomer). It is isolated from Olea europaea and Salvia canariensis and exhibits anti-inflammatory, antioxidant and antineoplastic activity. It has a role as an antioxidant, an antineoplastic agent, an anti-inflammatory agent and a plant metabolite. It is a pentacyclic triterpenoid and a dihydroxy monocarboxylic acid. It derives from a hydride of an oleanane.
Source: PubChem
US FDA substance register · UNII E233J88OHQ · registered name MASLINIC ACID · single chemical substance
Cosmetic roles
Safety & regulatory references
Other restriction: ban substances that deplete the ozone layer
Source: EU CosIng ingredient list
More data — names, identifiers, properties, test records, literature
Official labels & definitions
JCIA labelling name マスリン酸: 本品は、次の化学式で表される有機化合物である。
Source: JCIA labelling names (Japan)
Names & identifiers
- CAS No.chemical registry number
- 4373-41-5
- DTXSIDUS EPA chemical ID
- DTXSID30905074
- DTXCIDUS EPA compound ID
- DTXCID101334176
- IUPAC
- 2alpha,3beta-Dihydroxyolean-12-en-28-oic acid
- Molecular formula
- C30H48O4
- Molecular weight
- 472.71 g/mol
Measured properties
- Appearance
- Solid · Crystalline solid
- Melting point
- 249 - 250 °C
- Solubility
- Solubility of 0.3 mg/mL in a 1:2 solution of Ethanol:Buffered Water (pH 7.2) at 25 °C · In ethanol: 0.5 mg/mL, in DMSO: 20 mg/mL, in dimethyl formamide: 15 mg/mL
- Density
- 1.15 g/cu cm
Values measured on the substance itself, not a specification for a commercial raw material.
Source: PubChem
What products actually use it for
What the 2 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Softener and conditioner1
- Antioxidant1
Source: US EPA CompTox dashboard
Related literature
- Pentacyclic Triterpenoid Maslinic Acid Promotes Hair Growth Comparable to Minoxidil: A New Insight on the Potential Involvement of Cilia Activity · 2025
- Maslinic acid attenuates UVB‐induced oxidative damage in HFF‐1 cells · 2023
- Maslinic acid supplementation prevents di(2-ethylhexyl) phthalate-induced apoptosis via PRDX6 in peritubular myoid cells of Chinese forest musk deer. · 2023
- Biological Effects of Maslinic Acid on Human Epithelial Cells Used in Tissue Engineering · 2022
- The effect of maslinic acid on apoptotic genes in u266 multiple myeloma cell line · 2019
Linked databases 15
- ChEBI
- ChEMBL
- EU CosIng ingredient list 2
- JCIA labelling names (Japan)
- Korea Cosmetic Association ingredient dictionary
- MFDS (Korea) cosmetic ingredient register 2
- PubChem 2
- Tlooto literature search 2 3 4 5
- UniChem cross-reference IDs
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata
- Wikipedia · English · Chinese