(-)-menthone is a menthone that is cyclohexanone substituted by a methyl and an isopropyl group at positions 5 and 2 respectively (the 2S,5R-stereoisomer).
定义
(-)-menthone is a menthone that is cyclohexanone substituted by a methyl and an isopropyl group at positions 5 and 2 respectively (the 2S,5R-stereoisomer). It is an enantiomer of a (+)-menthone.
来源: PubChem
美国FDA 物质登记 · UNII 9NH5J4V8FN · 登记名称 MENTHONE, (±)- · 混合物
化妆品中的作用
安全与法规参考
Other restriction: ban substances that deplete the ozone layer
来源: 欧盟 CosIng 成分清单
详细资料——标示名称、识别编号、物性、试验记录、文献
官方标示名称和定义
日本化妆品工业联合会标示名称 メントン: 本品は、次の化学式で表される有機化合物である。
来源: 日本化妆品工业联合会标示名称
别名和识别信息
- CAS No.化学物质登记号
- 491-07-6
- CAS No.化学物质登记号
- 89-80-5
- EC No.欧盟化学品目录编号
- 201-941-1
- DTXSID美国EPA化学品编号
- DTXSID2044478
- DTXCID美国EPA化合物编号
- DTXCID201770739
- IUPAC
- (2S,5R)-5-Methyl-2-(propan-2-yl)cyclohexan-1-one
- 分子式
- C10H18O
- 分子量
- 154.253 g/mol
实测物性
- 性状
- Liquid · Colorless liquid with a mild odor of peppermint, [Hawley]
- 气味
- Slight peppermint odor · CHARACTERISTIC ODOR SIMILAR TO MENTHOL
- 沸点
- 210 °C · 207.00 to 210.00 °C. @ 760.00 mm Hg
- 熔点
- -6 °C
- 溶解性
- Slightly sol in water, sol in org solvents /L-form/ · SOL IN ALC, ETHER, ACETONE, ACETIC ACID, ALL PROP IN BENZENE, SLIGHTLY SOL IN WATER /D & DL-FORMS/
- 密度
- 0.888-0.895
这是对物质本身测得的数值，并非原料商品的规格。
来源: PubChem
产品实际使用的用途
这是向美国 EPA 申报含该成分的 48 款产品的用途。其中包括化妆品以外的产品，排在前几行的即为该成分的主要用途。
- Fragrance45
- Flavouring and nutrient3
来源: 美国EPA CompTox
刺激与致敏试验记录
记录有皮肤试验 3 项、眼部试验 1 项。
各项试验结论不一（最多的结论占 20%），因此不能断定该成分有刺激性。 这是对原料本身的试验记录，与成品中所含浓度下的刺激性不同。
查看全部 4 项试验
- Not likely to be sensitizing
skin sensitisation · Screening · according to other guideline: as mentioned below - Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · other guideline: as mentioned below according to - Moderate or Mild Irritation
skin irritation: in vivo · Screening · other guideline: as mentioned below according to - Studies Indicate No Significant Irritation
eye irritation: in vivo · Screening · other guideline: as mentioned below according to
来源: 美国EPA CompTox
相关文献
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- Menthol, Balance of Menthol/Menthone, and Essential Oil Contents of Mentha × Piperita L. under Foliar-Applied Chitosan and Inoculation of Arbuscular Mycorrhizal Fungi · 2020
- Effect of Different Skin Penetration Promoters in Halobetasol Propionate Permeation and Retention in Human Skin · 2017
- The application of anethole, menthone, and eugenol in transdermal penetration of valsartan: Enhancement and mechanistic investigation · 2016