Ingredient Dictionary

MENTHONE

(-)-menthone is a menthone that is cyclohexanone substituted by a methyl and an isopropyl group at positions 5 and 2 respectively (the 2S,5R-stereoisomer).

Definition

(-)-menthone is a menthone that is cyclohexanone substituted by a methyl and an isopropyl group at positions 5 and 2 respectively (the 2S,5R-stereoisomer). It is an enantiomer of a (+)-menthone.

Source: PubChem

US FDA substance register · UNII 9NH5J4V8FN · registered name MENTHONE, (±)- · mixture

Source: US FDA Unique Ingredient Identifier (UNII)

Cosmetic roles

Gives the product a scentPERFUMING

Safety & regulatory references

Other restriction: ban substances that deplete the ozone layer

Source: EU CosIng ingredient list

More data — names, identifiers, properties, test records, literature

Official labels & definitions

JCIA labelling name メントン: 本品は、次の化学式で表される有機化合物である。

Source: JCIA labelling names (Japan)

Names & identifiers

MENTHONEINCI멘톤Korean label name (MFDS standard)Cyclohexanone, 5-methyl-2-(1-methylethyl)-, (2R,5S)-rel-SynonymメントンJapanese labelling name

CAS No.chemical registry number: 491-07-6
CAS No.chemical registry number: 89-80-5
EC No.EU chemical inventory number: 201-941-1
DTXSIDUS EPA chemical ID: DTXSID2044478
DTXCIDUS EPA compound ID: DTXCID201770739

IUPAC: (2S,5R)-5-Methyl-2-(propan-2-yl)cyclohexan-1-one
Molecular formula: C10H18O
Molecular weight: 154.253 g/mol

Measured properties

Appearance: Liquid · Colorless liquid with a mild odor of peppermint, [Hawley]
Odour: Slight peppermint odor · CHARACTERISTIC ODOR SIMILAR TO MENTHOL
Boiling point: 210 °C · 207.00 to 210.00 °C. @ 760.00 mm Hg
Melting point: -6 °C
Solubility: Slightly sol in water, sol in org solvents /L-form/ · SOL IN ALC, ETHER, ACETONE, ACETIC ACID, ALL PROP IN BENZENE, SLIGHTLY SOL IN WATER /D & DL-FORMS/
Density: 0.888-0.895

Values measured on the substance itself, not a specification for a commercial raw material.

Source: PubChem

What products actually use it for

What the 48 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.

Fragrance45
Flavouring and nutrient3

Source: US EPA CompTox dashboard

Irritation and sensitisation studies

3 skin studies and 1 eye studies are on record.

Classed as moderate1Classed as low4

The studies disagree (the most common conclusion covers 20%), so they do not establish that this ingredient is irritating. These tests are on the raw material itself; irritation at the amount in a finished product is a different question.

See all 4 studies

Not likely to be sensitizing
skin sensitisation · Screening · according to other guideline: as mentioned below
Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · other guideline: as mentioned below according to
Moderate or Mild Irritation
skin irritation: in vivo · Screening · other guideline: as mentioned below according to
Studies Indicate No Significant Irritation
eye irritation: in vivo · Screening · other guideline: as mentioned below according to