Definition
US FDA substance register · UNII LF3LEI45OH · registered name MENTHYL ACETATE, (±)- · single chemical substance
Cosmetic roles
More data — names, identifiers, properties, test records, literature
Official labels & definitions
JCIA labelling name 酢酸メンチル: 本品は、酢酸とメントールのエステルであり、次の化学式で表される。
Source: JCIA labelling names (Japan)
Names & identifiers
- CAS No.chemical registry number
- 16409-45-3
- CAS No.chemical registry number
- 89-48-5
- EC No.EU chemical inventory number
- 201-911-8
- EC No.EU chemical inventory number
- 240-459-6
- DTXSIDUS EPA chemical ID
- DTXSID9041817
- DTXCIDUS EPA compound ID
- DTXCID701510704
- IUPAC
- (1R,2S,5R)-5-Methyl-2-(propan-2-yl)cyclohexyl acetate
- Molecular formula
- C12H22O2
- Molecular weight
- 198.306 g/mol
Measured properties
- Appearance
- liquid
- Colour
- colourless
- Melting/freezing point
- -20 ℃
- Initial boiling point and range
- 229.9 ℃(101.3 kPa)
- Flash point
- 89 ℃(101.3 kPa)
- Vapour pressure
- 26 ㎩ (25℃::01)
- Water solubility
- 17 g/㎖ (25℃::01)
- Relative density
- 0.922 (25 °CSigma-aldrich)
- n-Octanol/water partition coefficient (Kow)
- 10000 (20℃::01)
- Auto-ignition temperature
- 280 ℃
- Viscosity
- 3.95 cP (23 °C)
- Molecular weight
- 198.3
Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.
Source: KOSHA safety data sheets (Korea)
What products actually use it for
What the 9 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Deodorizer3
- Fragrance3
- Flavouring and nutrient2
- Adhesion/cohesion promoter1
Source: US EPA CompTox dashboard
Irritation and sensitisation studies
1 skin studies and 1 eye studies are on record.
The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.
See all 2 studies
- Not likely to be sensitizing
skin sensitisation: in vivo (LLNA) · Screening · according to OECD Guideline 429 (Skin Sensitisation: Local Lymph Node Assay) - Studies Indicate No Significant Irritation
eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) from February 1987 according to EU Method B.5 (Acute Toxicity: Eye Irritation / Corrosion) from January 1997 according to
Source: US EPA CompTox dashboard
Related literature
- Relationship between structural properties and biological activity of (-)-menthol and some menthyl esters · 2025
- Cytotoxic Activity of Cunila angustifolia Essential Oil · 2020
- Formaldehyde in Hypoallergenic Household Gloves · 2019
- Antimicrobial activity of five essential oils from lamiaceae against multidrug-resistant Staphylococcus aureus · 2018
- Chemical Profile and Extraction Technique of Oil of Mentha Arvensis · 2017
Linked databases 14
- Australian Industrial Chemicals Inventory (AICIS)
- China inventory of existing ingredients (IECIC)
- EU CosIng ingredient list 2
- JCIA labelling names (Japan)
- Korea Cosmetic Association ingredient dictionary
- KOSHA safety data sheets (Korea)
- MFDS (Korea) cosmetic ingredient register 2
- NIST Chemistry WebBook
- Tlooto literature search 2 3 4 5
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata