Definition
US FDA substance register · UNII E4K1LR90ZN · registered name METHACRYLAMIDOPROPYLTRIMETHYLAMMONIUM CHLORIDE · single chemical substance
Methacrylamidopropyltrimonium Chloride is the quaternary ammonium salt that conforms to the formula:
Cosmetic roles
Safety & regulatory references
Not classified under Korea’s toxic-substance GHS list · existing chemical substance
More data — names, identifiers, properties, test records, literature
Official labels & definitions
JCIA labelling name メタクリルアミドプロピルトリモニウムクロリド: 本品は、次の化学式で表される４級アンモニウム塩である。
Source: JCIA labelling names (Japan)
Names & identifiers
- CAS No.chemical registry number
- 51410-72-1
- DTXSIDUS EPA chemical ID
- DTXSID2044682
- DTXCIDUS EPA compound ID
- DTXCID0024682
- IUPAC
- N,N,N-Trimethyl-3-(2-methylprop-2-enamido)propan-1-aminium chloride
- Molecular formula
- C10H21ClN2O
- Molecular weight
- 220.74 g/mol
Measured properties
- Appearance
- Liquid · Solid, [ECHA REACH Registrations] 50% Aqueous solution: Yellowish liquid with almost no odor, [Evonik MSDS]
- Initial boiling point and range
- &, lt, 100 °C ℃
- Molecular weight
- 220.74
Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.
Source: PubChem · KOSHA safety data sheets (Korea)
What products actually use it for
What the 4 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Monomers2
- Softener and conditioner1
- Intermediate1
Source: US EPA CompTox dashboard
Irritation and sensitisation studies
2 skin studies and 1 eye studies are on record.
The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.
See all 3 studies
- Not likely to be sensitizing
skin sensitisation: in vivo (LLNA) · Screening · according to OECD Guideline 429 (Skin Sensitisation: Local Lymph Node Assay) adopted 24 April 2002 - Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · other guideline: Appraisal of the safety of chemicals in foods, druge and cosmetics, by the Staft of the Division of Pharmacology, US FDA, skin toxicity according to Draize (1959) according to other guideline: US FHSA Federal regulation: 16 CFR 1500.41 equivalent or similar to - Studies Indicate No Significant Irritation
eye irritation: in vivo · Screening · other guideline: US FHSA Federal regulation: 16 CFR 1500.42 according to OECD Guideline 405 (Acute Eye Irritation / Corrosion) equivalent or similar to
Source: US EPA CompTox dashboard
Linked databases 14
- AICIS inventory notices (Australia)
- Australian Industrial Chemicals Inventory (AICIS)
- ChEMBL
- EU CosIng ingredient list 2
- JCIA labelling names (Japan)
- Korea toxic substances GHS register (NIER)
- KOSHA safety data sheets (Korea)
- PubChem
- UniChem cross-reference IDs
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata