4-methoxyacetophenone is a member of the class of acetophenones that is acetophenone substituted by a methoxy group at position 4.
Definition
4-methoxyacetophenone is a member of the class of acetophenones that is acetophenone substituted by a methoxy group at position 4. It is a member of acetophenones and a monomethoxybenzene.
Source: PubChem
US FDA substance register · UNII 0IRH2BR587 · registered name 4-ACETYLANISOLE · single chemical substance
Cosmetic roles
Safety & regulatory references
Not classified under Korea’s toxic-substance GHS list · existing chemical substance
More data — names, identifiers, properties, test records, literature
Names & identifiers
- CAS No.chemical registry number
- 100-06-1
- EC No.EU chemical inventory number
- 202-815-9
- DTXSIDUS EPA chemical ID
- DTXSID2044347
- DTXCIDUS EPA compound ID
- DTXCID0024347
- IUPAC
- 1-(4-Methoxyphenyl)ethan-1-one
- Molecular formula
- C9H10O2
- Molecular weight
- 150.177 g/mol
Measured properties
- Appearance
- CBI · White crystalline powder, mp = 36-40 deg C, [Alfa Aesar MSDS]
- Odour
- Pleasant odor · Hawthorn odor
- Boiling point
- 254 °C · 152.00 to 154.00 °C. @ 26.00 mm Hg
- Melting point
- 38.2 °C · 38 - 39 °C
- Solubility
- Soluble in ethanol, diethyl ether, acetone and chloroform · Soluble in alcohol, ether, fixed oils
- Density
- 1.0818 g/cu cm at 41 °C
- Stability
- Stable under recommended storage conditions.
- Colour
- white
- Melting/freezing point
- 38.5 ℃
- Initial boiling point and range
- 258 ℃
- Vapour pressure
- 0.00644 ㎜Hg (@ 25 ℃)
- Water solubility
- 2470 ㎎/ℓ (@ 25 ℃, est.)
- Vapour density
- 5.18
- n-Octanol/water partition coefficient (Kow)
- 1.74
- Molecular weight
- 150.18
Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.
Source: PubChem · KOSHA safety data sheets (Korea)
What products actually use it for
What the 9 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Fragrance6
- Flavouring and nutrient2
- No specific technical function1
Source: US EPA CompTox dashboard
Related literature
- Photo‐Aggravated Allergic Contact Dermatitis due to Hydroxyacetophenone Present in a Sunscreen: A Case Report · 2025
- Fate of UV filter Ethylhexyl methoxycinnamate in rat model and human urine: Metabolism, exposure and demographic associations. · 2019
- Safety and efficacy of aromatic ketones, secondary alcohols and related esters belonging to chemical group 21 when used as flavourings for all animal species · 2016
- Use of an Ex Vivo Local Lymph Node Assay to Assess Contact Hypersensitivity Potential · 2008
Linked databases 16
- Australian Industrial Chemicals Inventory (AICIS)
- ChEBI
- ChEMBL
- EU CosIng ingredient list 2
- Korea toxic substances GHS register (NIER)
- KOSHA safety data sheets (Korea)
- NIST Chemistry WebBook
- PubChem 2
- Tlooto literature search 2 3 4
- UniChem cross-reference IDs
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata
- Wikipedia · English · Japanese · Chinese