Ethylene Glycol Monomethyl Ether Acetate can cause developmental toxicity and male reproductive toxicity according to The National Institute for Occupational Safety and Health (NIOSH).
Definition
Ethylene Glycol Monomethyl Ether Acetate can cause developmental toxicity and male reproductive toxicity according to The National Institute for Occupational Safety and Health (NIOSH).
Source: PubChem
US FDA substance register · UNII I62493E04O · registered name Methoxyethanol Acetate · single chemical substance
Cosmetic roles
Safety & regulatory references
- Banned
- Argentina · ASEAN · Brazil · Canada · China · European Union · South Korea · Taiwan
Source: ASEAN Cosmetic Directive · Health Canada Cosmetic Ingredient Hotlist · MFDS (Korea) cosmetic regulatory information
Not classified under Korea’s toxic-substance GHS list · existing chemical substance
EU Cosmetics Regulation, Annex II (prohibited substances), entry 672
Health Canada Cosmetic Ingredient Hotlist · prohibited in cosmetics
Restriction II/662
Source: EU CosIng ingredient list
More data — names, identifiers, properties, test records, literature
Names & identifiers
- CAS No.chemical registry number
- 110-49-6
- EC No.EU chemical inventory number
- 203-772-9
- DTXSIDUS EPA chemical ID
- DTXSID2025553
- DTXCIDUS EPA compound ID
- DTXCID205553
- IUPAC
- 2-Methoxyethyl acetate
- Molecular formula
- C5H10O3
- Molecular weight
- 118.132 g/mol
Measured properties
- Appearance
- liquid
- Colour
- colourless
- Melting/freezing point
- -70 ℃
- Initial boiling point and range
- 143 ℃
- Flash point
- 45 ℃
- Upper/lower flammability or explosive limits
- 12.3 / 1.5 %
- Vapour pressure
- 0.27 ㎪ (20℃)
- Vapour density
- 4.1
- Relative density
- 3.39 (21.8℃)
- n-Octanol/water partition coefficient (Kow)
- 0.121
- Auto-ignition temperature
- 380 ℃
- Molecular weight
- 118.1311
Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.
Source: KOSHA safety data sheets (Korea)
What products actually use it for
What the 3 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Solvent1
- Viscosity modifier1
- Fragrance1
Source: US EPA CompTox dashboard
Irritation and sensitisation studies
2 skin studies and 2 eye studies are on record.
The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.
See all 4 studies
- Classification not possible
Skin Sensitization · Screening - Not classified
Skin Irritation · Screening - Category 2B
Eye Irritation · Screening - Category 6.4A (Category 2A)
Eye Irritation · Read Across
Source: US EPA CompTox dashboard
Related literature
Linked databases 17
- ASEAN Cosmetic Directive
- Australian Industrial Chemicals Inventory (AICIS)
- EU CosIng ingredient list 2
- EU prohibited substances (Annex II)
- Health Canada Cosmetic Ingredient Hotlist
- Korea toxic substances GHS register (NIER)
- KOSHA safety data sheets (Korea)
- MFDS (Korea) cosmetic regulatory information 2 3
- NIST Chemistry WebBook
- PubChem
- Tlooto literature search
- UniChem cross-reference IDs
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata