Definition
US FDA substance register · UNII 515K4I683Y · registered name 2-METHOXYETHYL ACRYLATE · single chemical substance
Cosmetic roles
Safety & regulatory references
- Banned
- ASEAN · European Union · United Kingdom
Source: ASEAN Cosmetic Directive · EU Cosmetics Regulation · MFDS (Korea) cosmetic regulatory information · UK cosmetics regulations (OPSS)
Not classified under Korea’s toxic-substance GHS list · existing chemical substance
EU Cosmetics Regulation, Annex II (prohibited substances), entry 1668
More data — names, identifiers, properties, test records, literature
Official labels & definitions
JCIA labelling name アクリル酸メトキシエチル: 本品は、次の化学式で表される有機化合物である。
Source: JCIA labelling names (Japan)
Names & identifiers
- CAS No.chemical registry number
- 3121-61-7
- EC No.EU chemical inventory number
- 221-499-3
- EC No.EU chemical inventory number
- 221-499-3 (I)
- DTXSIDUS EPA chemical ID
- DTXSID7025554
- DTXCIDUS EPA compound ID
- DTXCID605554
- IUPAC
- 2-Methoxyethyl prop-2-enoate
- Molecular formula
- C6H10O3
- Molecular weight
- 130.143 g/mol
Measured properties
- Appearance
- liquid
- Melting/freezing point
- &, lt, -30 ℃
- Initial boiling point and range
- 67 ℃
- Flash point
- 56 ℃
- Vapour pressure
- 4 ㎜Hg(at 25 C)
- Water solubility
- 19040 ㎎/ℓ(at 25C est.)
- Relative density
- 1.012 (at 20 C)
- n-Octanol/water partition coefficient (Kow)
- 0.8
- Auto-ignition temperature
- 402 ℃
- Molecular weight
- 130
Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.
Source: KOSHA safety data sheets (Korea)
What products actually use it for
What the 2 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Film former1
- Monomers1
Source: US EPA CompTox dashboard
Irritation and sensitisation studies
6 skin studies and 3 eye studies are on record.
The studies disagree (the most common conclusion covers 50%), so they do not establish that this ingredient is irritating. These tests are on the raw material itself; irritation at the amount in a finished product is a different question.
See all 9 studies
- Category 2
Skin Irritation · Screening - SkinSens1
Skin Sensitization · QSAR Predicted - Category 6.3A (Category 2)
Skin Irritation · Read Across - SkinIrr2
Skin Irritation · QSAR Predicted - Classification not possible
Skin Sensitization · Screening - High Frequency of Sensitization
skin sensitisation: in vivo (LLNA) · Screening · according to OECD Guideline 429 (Skin Sensitisation: Local Lymph Node Assay) according to EU Method B.42 (Skin Sensitisation: Local Lymph Node Assay) - Category 6.4A (Category 2A)
Eye Irritation · Read Across - Category 2A
Eye Irritation · Screening - Corrosive or Irritation Persists for > 21 days
eye irritation: in vivo · Screening · other guideline: EPA 40 CFR 163.81.4 equivalent or similar to OECD Guideline 405 (Acute Eye Irritation / Corrosion) equivalent or similar to
Source: US EPA CompTox dashboard
Related literature
Linked databases 19
- ASEAN Cosmetic Directive
- Australian Industrial Chemicals Inventory (AICIS)
- EU CosIng ingredient list 2
- EU Cosmetics Regulation
- EU prohibited substances (Annex II)
- JCIA labelling names (Japan)
- Korea Cosmetic Association ingredient dictionary
- Korea toxic substances GHS register (NIER)
- KOSHA safety data sheets (Korea)
- MFDS (Korea) cosmetic ingredient register 2
- MFDS (Korea) cosmetic regulatory information 2 3
- Tlooto literature search 2
- UK cosmetics regulations (OPSS)
- UniChem cross-reference IDs
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata