How much products actually contain
No product states its amount yet.
Of the products containing it, 0 list it before the 1% line and 1 after it (usually 1% or less).
Products using this ingredient
1 of 1 confirmed · likeliest to carry enough first
Definition
US FDA substance register · UNII 74Z7JO8V3U · registered name METHOXYISOPROPANOL · single chemical substance
Cosmetic roles
Safety & regulatory references
Canada
- Maximum Concentration Permitted : 0.5% of 2-methoxypropanol (1589-47-5)
Source: MFDS (Korea) cosmetic regulatory information
Not classified under Korea’s toxic-substance GHS list · existing chemical substance
Other restriction: ban substances that deplete the ozone layer
Source: EU CosIng ingredient list
Reviewed by CIR: Final Report on the Safety Assessment of Methoxyisopropanol and Methoxyisopropyl Acetate as Used in Cosmetics
More data — names, identifiers, properties, test records, literature
Official labels & definitions
JCIA labelling name メトキシイソプロパノール: 本品は、次の化学式で表される脂肪族エーテルアルコールである。
Source: JCIA labelling names (Japan)
Names & identifiers
- CAS No.chemical registry number
- 107-98-2
- EC No.EU chemical inventory number
- 203-539-1
- DTXSIDUS EPA chemical ID
- DTXSID8024284
- DTXCIDUS EPA compound ID
- DTXCID804284
- IUPAC
- 1-Methoxypropan-2-ol
- Molecular formula
- C4H10O2
- Molecular weight
- 90.122 g/mol
Measured properties
- Appearance
- liquid
- Colour
- colourless
- Melting/freezing point
- -95 ℃
- Initial boiling point and range
- 119 ℃
- Flash point
- 38 ℃
- Evaporation rate
- 0.7
- Upper/lower flammability or explosive limits
- 13.1 / 1.9 %
- Vapour pressure
- 12.5 ㎜Hg (25℃)
- Water solubility
- 1 000 000 ㎎/ℓ (&, gt, ,20℃)
- Vapour density
- 3.11
- Relative density
- 0.962 (20℃)
- n-Octanol/water partition coefficient (Kow)
- -0.49 (est.)
- Auto-ignition temperature
- 287 ℃ (101.3 hPa)
- Decomposition temperature
- 556 (kcal/mol)
- Viscosity
- 1.81 (20℃, mPa s)
- Molecular weight
- 90.13
Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.
Source: KOSHA safety data sheets (Korea)
What products actually use it for
What the 73 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Solvent24
- No specific technical function6
- Fragrance5
- Solubility enhancer4
- Pigment4
- Surfactant (surface active agent)4
- Processing aids not otherwise specified4
- Dispersing agent3
10 other uses
- Intermediate3
- Chemical reaction regulator3
- Viscosity modifier3
- Corrosion inhibitor2
- UV stabilizer2
- Diluent2
- Photosensitive agent1
- Sealant (barrier)1
- Coalescing agent1
- Cleaning agent1
Source: US EPA CompTox dashboard
Irritation and sensitisation studies
8 skin studies and 3 eye studies are on record.
The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.
See all 11 studies
- Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · EU Method B.4 (Acute Toxicity: Dermal Irritation / Corrosion) equivalent or similar to - Category 6.3B (Category 3)
Skin Irritation · Read Across - Classification not possible
Skin Sensitization · Screening - Not likely to be sensitizing
skin sensitisation: in vivo (non-LLNA) · Screening · equivalent or similar to EU Method B.6 (Skin Sensitisation) - Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) equivalent or similar to - Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) according to EU Method B.4 (Acute Toxicity: Dermal Irritation / Corrosion) according to - Not classified
Skin Irritation · Screening - Not likely to be sensitizing
skin sensitisation · Screening · according to other guideline: Modification of the method of Maguire (1973) - Category 6.4A (Category 2A)
Eye Irritation · Read Across - Category 2B
Eye Irritation · Screening - Studies Indicate No Significant Irritation
eye irritation: in vivo · Screening · EU Method B.5 (Acute Toxicity: Eye Irritation / Corrosion) equivalent or similar to
Source: US EPA CompTox dashboard
Related literature
- Final Report on the Safety Assessment of Methoxyisopropanol and Methoxyisopropyl Acetate as Used in Cosmetics · 2008
- Final Report of the Cosmetic Ingredient Review Expert Panel Safety Assessment of Methoxyisopropanol · 2004
- Final Report of the Cosmetic Ingredient Review Expert Panel Safety Assessment of Methoxyisopropanol and Methoxyisopropyl Acetate September 10 , 2004 · 2004
Linked databases 21
- Australian Industrial Chemicals Inventory (AICIS)
- ChEMBL
- China inventory of existing ingredients (IECIC)
- EU CosIng ingredient list 2
- Health Canada Cosmetic Ingredient Hotlist
- JCIA labelling names (Japan)
- Korea Cosmetic Association ingredient dictionary
- Korea toxic substances GHS register (NIER)
- KOSHA safety data sheets (Korea)
- MFDS (Korea) cosmetic ingredient register 2
- MFDS (Korea) cosmetic regulatory information 2 3 4
- NIST Chemistry WebBook
- Tlooto literature search 2 3
- UniChem cross-reference IDs
- US Cosmetic Ingredient Review (CIR) 2
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata
- Wikipedia · English · Japanese · Chinese