Ingredient Dictionary

METHYL AMYL KETONE

Heptan-2-one is a dialkyl ketone with methyl and pentyl as the alkyl groups.

Definition

Heptan-2-one is a dialkyl ketone with methyl and pentyl as the alkyl groups. It has a role as a pheromone and a mouse metabolite. It is a dialkyl ketone and a methyl ketone.

Source: PubChem

US FDA substance register · UNII 89VVP1B008 · registered name 2-Heptanone · single chemical substance

Source: US FDA Unique Ingredient Identifier (UNII)

Cosmetic roles

Gives the product a scentPERFUMING

Safety & regulatory references

Not classified under Korea’s toxic-substance GHS list · existing chemical substance

Source: Korea toxic substances GHS register (NIER)

More data — names, identifiers, properties, test records, literature

Names & identifiers

METHYL AMYL KETONEINCI2-HeptanoneSynonym

CAS No.chemical registry number: 110-43-0
EC No.EU chemical inventory number: 203-767-1
DTXSIDUS EPA chemical ID: DTXSID5021916
DTXCIDUS EPA compound ID: DTXCID601916

IUPAC: Heptan-2-one
Molecular formula: C7H14O
Molecular weight: 114.188 g/mol

Measured properties

Appearance: N-amyl methyl ketone appears as a clear colorless liquid. Flash point 126 °F. Less dense than water and only slightly soluble in water. Hence floats on water. Vapors heavier than air. Density 6.8 lb / gal. Used as a synthetic flavoring and in perfumes. · CBI, Liquid
Odour: Penetrating fruity odor · CHARACTERISTIC BANANA, SLIGHTLY SPICY ODOR
Boiling point: 300 °F at 760 mmHg (USCG, 1999) · 151.5 °C at 760 mm Hg, 111 °C at 21 mm Hg
Melting point: -31 °F (USCG, 1999) · -35.5 °C
Solubility: 0.4 % (NIOSH, 2024) · Soluble in alcohol and ether
Density: 0.82 (USCG, 1999) - Less dense than water, will float · 0.8324 at 0 °C/4 °C, 0.8197 at 15 °C/4 °C, 0.8068 at 30 °C/4 °C
Colour: colourless
Melting/freezing point: -20 ℃
Initial boiling point and range: 148 ℃
Flash point: 41 ℃(at 101.41 kPa)
Upper/lower flammability or explosive limits: 5.5 / 1 %
Vapour pressure: 918 ㎩(25℃)
Water solubility: 4.21 g/ℓ(20℃, g/L)
Relative density: 0.814 (20℃)
n-Octanol/water partition coefficient (Kow): 2.26 (30℃)
Auto-ignition temperature: 358 ℃
Viscosity: 0.979 ㎡/s(20℃)
Molecular weight: 114.1866

Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.

Source: PubChem · KOSHA safety data sheets (Korea)

What products actually use it for

What the 22 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.

Solvent10
Fragrance4
Processing aids not otherwise specified2
Flavouring and nutrient2
Fuel1
Intermediate1
Cleaning agent1
Binder1

Source: US EPA CompTox dashboard

Irritation and sensitisation studies

6 skin studies and 3 eye studies are on record.

Classed as moderate2Classed as low1

The study conclusions largely agree (67%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.

See all 9 studies

Classification not possible
Skin Sensitization · Screening
Not likely to be sensitizing
skin sensitisation: in vivo (LLNA) · Screening · according to OECD Guideline 429 (Skin Sensitisation: Local Lymph Node Assay) according to EU Method B.42 (Skin Sensitisation: Local Lymph Node Assay)
Skin corrosion/irritation - Category 2
Skin Irritation · Screening
Classification not possible
Skin Irritation · Screening
Category 6.3B (Category 3)
Skin Irritation · Read Across
Moderate or Mild Irritation
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) according to
Category 6.4A (Category 2A)
Eye Irritation · Read Across
Category 2B
Eye Irritation · Screening
Moderate or Mild Irritation
eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) according to EU Method B.5 (Acute Toxicity: Eye Irritation / Corrosion) according to