Methyl phenylglyoxalate is the methyl ester of phenylglyoxylic acid with methanol.
Definition
US FDA substance register · UNII 23F2045STG · registered name METHYL PHENYLGLYOXALATE · single chemical substance
Methyl phenylglyoxalate is the methyl ester of phenylglyoxylic acid with methanol. Metabolite observed in cancer metabolism. It has a role as a human metabolite. It is a methyl ester and an alpha-ketoester. It is functionally related to a phenylglyoxylic acid.
Source: PubChem
Cosmetic roles
Safety & regulatory references
Not classified under Korea’s toxic-substance GHS list · existing chemical substance
More data — names, identifiers, properties, test records, literature
Official labels & definitions
JCIA labelling name ベンゾイルギ酸メチル: 本品は、次の化学式で表される有機化合物である。
Source: JCIA labelling names (Japan)
Names & identifiers
- CAS No.chemical registry number
- 15206-55-0
- EC No.EU chemical inventory number
- 239-263-3
- DTXSIDUS EPA chemical ID
- DTXSID9065867
- DTXCIDUS EPA compound ID
- DTXCID1034927
- IUPAC
- Methyl oxo(phenyl)acetate
- Molecular formula
- C9H8O3
- Molecular weight
- 164.16 g/mol
What products actually use it for
What the 8 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Photosensitizers6
- Softener and conditioner1
- Catalyst1
Source: US EPA CompTox dashboard
Irritation and sensitisation studies
3 skin studies and 1 eye studies are on record.
The studies disagree (the most common conclusion covers 33%), so they do not establish that this ingredient is irritating. These tests are on the raw material itself; irritation at the amount in a finished product is a different question.
See all 4 studies
- High Frequency of Sensitization
skin sensitisation: in vitro · Screening · according to other guideline: DRAFT OECD in vitro skin sensitisation: U-937 skin sensitisation test (U-SENS) Draft - Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · other guideline: Federal Register 38, No. 187, s1500.41, S. 27029 (1973) according to - Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · other guideline: Federal Register 38, No. 187, s1500.41, S. 27029 1973 according to - Studies Indicate No Significant Irritation
eye irritation: in vivo · Screening · other guideline: Federal Register 38, No. 187, s1500.41, S. 27019 vom 27.09.73 according to OECD Guideline 405 (Acute Eye Irritation / Corrosion) equivalent or similar to
Source: US EPA CompTox dashboard
Linked databases 13
- Australian Industrial Chemicals Inventory (AICIS)
- ChEBI
- EU CosIng ingredient list 2
- JCIA labelling names (Japan)
- Korea toxic substances GHS register (NIER)
- NIST Chemistry WebBook
- PubChem
- UniChem cross-reference IDs
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata