Methyl cinnamate is a methyl ester resulting from the formal condensation of methyl cinnamic acid with methanol.
定义
Methyl cinnamate is a methyl ester resulting from the formal condensation of methyl cinnamic acid with methanol. It is found naturally in the essential oils of Alpinia and Basil leaf oil, and widely used in the flavor and perfume industries. It has a role as an insect attractant, a volatile oil component, a flavouring agent, a fragrance and an anti-inflammatory agent. It is an alkyl cinnamate and a methyl ester.
来源: PubChem
美国FDA 物质登记 · UNII 533CV2ZCQL · 登记名称 METHYL CINNAMATE · 单一化学物质
化妆品中的作用
安全与法规参考
未列入韩国有毒物质 GHS 分类 · 现有化学物质
详细资料——标示名称、识别编号、物性、试验记录、文献
别名和识别信息
- CAS No.化学物质登记号
- 103-26-4
- EC No.欧盟化学品目录编号
- 203-093-8
- DTXSID美国EPA化学品编号
- DTXSID6042151
- DTXCID美国EPA化合物编号
- DTXCID5028118
- IUPAC
- Methyl 3-phenylprop-2-enoate
- 分子式
- C10H10O2
- 分子量
- 162.188 g/mol
实测物性
- 性状
- Liquid · Solid with a fruity, balsamic odor like strawberries, mp = 36 deg C, [Merck Index] Light yellow crystals, mp = 36-38 deg C, [Sigma-Aldrich MSDS]
- 沸点
- 262-263 °C
- 溶解性
- insoluble in water, soluble in oils · moderately soluble (in ethanol)
- 熔点/凝固点
- 31~38 ℃
- 初沸点和沸程
- 260~263 ℃
- 闪点
- &, gt, 110 ℃
- 蒸气压
- 0.011 ㎜Hg (25 C)
- 比重
- 1.042 (at 36℃)
- 正辛醇/水分配系数（Kow）
- 2.18
- 黏度
- 1.26 cP (100 C)
- 分子量
- 162.08
这是对物质本身测得的数值。韩国安全保健公团（KOSHA）的资料仅供编写和审核安全数据表参考，并非原料商品的规格。
来源: PubChem · 韩国安全保健公团 安全数据表
产品实际使用的用途
这是向美国 EPA 申报含该成分的 85 款产品的用途。其中包括化妆品以外的产品，排在前几行的即为该成分的主要用途。
- Fragrance80
- Flavouring and nutrient2
- Opacifer1
- Viscosity modifier1
- No specific technical function1
来源: 美国EPA CompTox
刺激与致敏试验记录
记录有皮肤试验 6 项、眼部试验 1 项。
各项试验结论不一（最多的结论占 57%），因此不能断定该成分有刺激性。 这是对原料本身的试验记录，与成品中所含浓度下的刺激性不同。
查看全部 7 项试验
- High Frequency of Sensitization
skin sensitisation: in vivo (non-LLNA) · Screening · according to OECD Guideline 406 (Skin Sensitisation) 1981 Edition - High Frequency of Sensitization
skin sensitisation: in vivo (non-LLNA) · Screening · according to other guideline: Kero, M., and Hannuksela, M. (1980). Guinea pig maximisation test, open epicutaneous test, and chamber test in the induction of delayed contact hypersensitivity. Contact Derm. 6, 341-344. - High Frequency of Sensitization
skin sensitisation: in vivo (non-LLNA) · Screening · according to OECD Guideline 406 (Skin Sensitisation) - Not likely to be sensitizing
skin sensitisation: in vivo (non-LLNA) · Screening · equivalent or similar to OECD Guideline 406 (Skin Sensitisation) - Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) equivalent or similar to - High Frequency of Sensitization
skin sensitisation: in vivo (non-LLNA) · Screening · according to other guideline: Kelcak G. (1983) Identification of contact allergens: predictive tests in animals. In: Marzulli FN, Maibach HI, (eds), Dermatoxicology, 2nd Ed., Hemisphere Ney York, pp 193-236. - Studies Indicate No Significant Irritation
eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) equivalent or similar to
来源: 美国EPA CompTox
相关文献
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