Definition
US FDA substance register · UNII 3IG3K131QJ · registered name Methyl diethanolamine · single chemical substance
Methyl Diethanolamine is the organic compound that conforms to the formula
Cosmetic roles
Safety & regulatory references
Not classified under Korea’s toxic-substance GHS list · existing chemical substance
More data — names, identifiers, properties, test records, literature
Official labels & definitions
JCIA labelling name メチルＤＥＡ: 本品は、次の化学式で表される有機化合物である。
Source: JCIA labelling names (Japan)
Names & identifiers
- CAS No.chemical registry number
- 105-59-9
- EC No.EU chemical inventory number
- 203-312-7
- DTXSIDUS EPA chemical ID
- DTXSID8025591
- DTXCIDUS EPA compound ID
- DTXCID605591
- IUPAC
- 2,2'-(Methylazanediyl)di(ethan-1-ol)
- Molecular formula
- C5H13NO2
- Molecular weight
- 119.164 g/mol
Measured properties
- Melting/freezing point
- -21 ℃
- Initial boiling point and range
- 247 ℃
- Flash point
- 136 ℃(c.c.)
- Upper/lower flammability or explosive limits
- 8.4 / 0.9 %
- Vapour pressure
- 0.053 ㎜Hg (25℃)
- Water solubility
- 100 g/100㎖
- Vapour density
- 4.12
- Relative density
- 1.04
- n-Octanol/water partition coefficient (Kow)
- -1.08
- Auto-ignition temperature
- 265 ℃
Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.
Source: KOSHA safety data sheets (Korea)
What products actually use it for
What the 16 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Processing aids not otherwise specified5
- Intermediate2
- Fragrance2
- Absorbent1
- Photosensitizers1
- Chemical reaction regulator1
- pH regulating agent1
- Film former1
2 other uses
- Preservative1
- Solvent1
Source: US EPA CompTox dashboard
Irritation and sensitisation studies
5 skin studies and 5 eye studies are on record.
The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.
See all 10 studies
- Category 6.3B (Category 3)
Skin Irritation · Read Across - Classification not possible
Skin Sensitization · Screening - Not likely to be sensitizing
skin sensitisation: in vivo (non-LLNA) · Screening · equivalent or similar to OECD Guideline 406 (Skin Sensitisation) - Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) equivalent or similar to - Not classified
Skin Irritation · Screening - Eye irritation - category 2A
Eye Irritation · Screening - Severe Irritation
eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) equivalent or similar to - Eye Irrit. 2
Eye Irritation · Authoritative - Category 6.4A (Category 2A)
Eye Irritation · Read Across - Category 2B
Eye Irritation · Screening
Source: US EPA CompTox dashboard
Related literature
Linked databases 17
- Australian Industrial Chemicals Inventory (AICIS)
- ChEMBL
- EU CosIng ingredient list 2
- JCIA labelling names (Japan)
- Korea Cosmetic Association ingredient dictionary
- Korea toxic substances GHS register (NIER)
- KOSHA safety data sheets (Korea)
- MFDS (Korea) cosmetic ingredient register 2
- NIST Chemistry WebBook
- Tlooto literature search 2
- UniChem cross-reference IDs
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata
- Wikipedia · English · Chinese