Ingredient Dictionary

METHYL EUGENOL

Methyleugenol can cause cancer according to The National Toxicology Program.

Definition

Methyleugenol can cause cancer according to The National Toxicology Program.

Source: PubChem

US FDA substance register · UNII 29T9VA6R7M · registered name METHYL EUGENOL · single chemical substance

Source: US FDA Unique Ingredient Identifier (UNII)

Cosmetic roles

Gives the product a scentPERFUMINGListed as a fragrance-composition material (not a claim that it adds scent)FRAGRANCE

Safety & regulatory references

Banned: ASEAN · China
Restricted or banned: Argentina · ASEAN · Brazil · South Korea
Restricted: International fragrance standard (IFRA) · United Kingdom

Source: ASEAN Cosmetic Directive · MFDS (Korea) cosmetic regulatory information · EU Cosmetics Regulation · Health Canada Cosmetic Ingredient Hotlist · IFRA fragrance standards · UK cosmetics regulations (OPSS)

Canada

Conditions of Use by product type : Permitted as a naturally occurring component in botanical extracts. a) Fine fragrances b) Eau de toilette c) In a fragrance cream d) Other leave-on products and in oral hygiene products e) Rinse-off products
Maximum Concentration Permitted : (a) 0.01% b) 0.004% c) 0.002% d) 0.0002% e) 0.001%

European Union

Product Type, body parts : (a) Fine fragrance (b) Eau de toilette (c) Fragrance cream (d) Other leave-on products and oral products (e) Rinse-off products
Maximum concentration in ready for use preparation : (a) 0.01% (b) 0.004% (c) 0.002% (d) 0.0002% (e) 0.001%

Source: MFDS (Korea) cosmetic regulatory information

Not classified under Korea’s toxic-substance GHS list · existing chemical substance

Source: Korea toxic substances GHS register (NIER)

EU Cosmetics Regulation, Annex III (restricted substances), entry 102 · maximum concentration (a) 0.01% (b) 0.004% (c) 0.002% (d) 0.0002% (e) 0.001% · applies to (a) Fine fragrance (b) Eau de toilette (c) Fragrance cream (d) Other leave-on products and oral products (e) Rinse-off products

Source: EU restricted substances (Annex III)

Restriction III/102 · Other restriction: ban substances that deplete the ozone layer

Source: EU CosIng ingredient list

More data — names, identifiers, properties, test records, literature

Official labels & definitions

JCIA labelling name メチルオイゲノール: 本品は、次の化学式で表される芳香族化合物である。

Source: JCIA labelling names (Japan)

Names & identifiers

METHYL EUGENOLINCI메틸유제놀Korean label name (MFDS standard)Benzene, 1,2-dimethoxy-4-(2-propenyl)-SynonymMETHYLEUGENOLSynonymメチルオイゲノールJapanese labelling name

CAS No.chemical registry number: 93-15-2
EC No.EU chemical inventory number: 202-223-0
DTXSIDUS EPA chemical ID: DTXSID5025607
DTXCIDUS EPA compound ID: DTXCID505607

IUPAC: 1,2-Dimethoxy-4-(prop-2-en-1-yl)benzene
Molecular formula: C11H14O2
Molecular weight: 178.231 g/mol

Measured properties

Appearance: Methyleugenol is a clear colorless to pale yellow liquid with a spicy earthy odor. Bitter burning taste. (NTP, 1992) · Liquid
Odour: Mild-spicy, slightly herbal odor · Clove, carnation odor
Boiling point: 490.5 °F at 760 mmHg (NTP, 1992) · 254.7 °C
Melting point: 25 °F (NTP, 1992) · -4 °C
Solubility: less than 1 mg/mL at 66 °F (NTP, 1992) · Soluble in most organic solvents
Density: 1.0396 at 68 °F (NTP, 1992) - Denser than water, will sink · 1.032-1.036 at 25 °C
Stability: Stable to air, heat and light.
Melting/freezing point: -4 ℃
Initial boiling point and range: 254.7 ℃
Flash point: 99 ℃(C.C.)
Vapour pressure: 0.012 ㎜Hg (25℃)
Water solubility: 0.05 g/100㎖ (25℃)
Vapour density: (&amp, gt, 1)
Relative density: 1.04 (20℃)
n-Octanol/water partition coefficient (Kow): 3.03 (est.)
Molecular weight: 178.23

Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.

Source: PubChem · KOSHA safety data sheets (Korea)

What products actually use it for

What the 16 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.

Fragrance14
Deodorizer2

Source: US EPA CompTox dashboard

Irritation and sensitisation studies

4 skin studies and 2 eye studies are on record.

Classed as low3

The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.

See all 6 studies

Not classified
Skin Irritation · Screening
Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) equivalent or similar to
Not likely to be sensitizing
skin sensitisation: in vivo (non-LLNA) · Screening · equivalent or similar to OECD Guideline 406 (Skin Sensitisation)
Classification not possible
Skin Sensitization · Screening
Studies Indicate No Significant Irritation
eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) equivalent or similar to
Category 2B
Eye Irritation · Screening