Ingredient Dictionary

METHYL ISOPROPYL KETONE

3-Methylbutan-2-one is a ketone.

Definition

3-Methylbutan-2-one is a ketone.

Source: PubChem

US FDA substance register · UNII V8DP6THY5O · registered name METHYL ISOPROPYL KETONE · single chemical substance

Source: US FDA Unique Ingredient Identifier (UNII)

Cosmetic roles

Gives the product a scentPERFUMING

Safety & regulatory references

Not classified under Korea’s toxic-substance GHS list · existing chemical substance

Source: Korea toxic substances GHS register (NIER)

More data — names, identifiers, properties, test records, literature

Names & identifiers

METHYL ISOPROPYL KETONEINCI2-Butanone, 3-methyl-Synonym

CAS No.chemical registry number: 563-80-4
EC No.EU chemical inventory number: 209-264-3
DTXSIDUS EPA chemical ID: DTXSID0022062
DTXCIDUS EPA compound ID: DTXCID802062

IUPAC: 3-Methylbutan-2-one
Molecular formula: C5H10O
Molecular weight: 86.134 g/mol

Measured properties

Appearance: 3-methylbutan-2-one appears as a colorless liquid with a pleasant odor. Flash point below 70 °F. Less dense than water. May be toxic by inhalation and skin absorption. Used as a solvent. · Liquid
Odour: The odor threshold lies between 1.9 and 3.1 ppm (6.8 and 11 mg/cu m). Acetone-like odor. · Acetone-like odor
Boiling point: 201 °F at 760 mmHg (USCG, 1999) · 94.33 °C
Melting point: -134 °F (USCG, 1999) · -93.1 °C
Solubility: Very slight (NIOSH, 2024) · Miscible with ethanol, ethyl ether, very soluble in acetone, soluble in carbon tetrachloride
Density: 0.8051 at 68 °F (USCG, 1999) - Less dense than water, will float · 0.8501 g/cu cm at 20 °C
Viscosity: 0.63 mm²/s at 16 °C · 0.454 (25 °C, mPa s, (dynamic))
Colour: colourless
Melting/freezing point: -92 ℃
Initial boiling point and range: 93~95 ℃
Flash point: -3 ℃
Upper/lower flammability or explosive limits: 8 / 1.2 %
Vapour pressure: 7028 ㎩ (25℃)
Water solubility: 8.21 ( 20℃, g/L)
Vapour density: 3
Relative density: 0.81
n-Octanol/water partition coefficient (Kow): 0.84
Auto-ignition temperature: 475 ℃
Molecular weight: 86.2

Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.

Source: PubChem · KOSHA safety data sheets (Korea)

What products actually use it for

What the 4 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.

Solvent1
Fragrance1
Intermediate1
Flavouring and nutrient1

Source: US EPA CompTox dashboard

Irritation and sensitisation studies

2 skin studies and 1 eye studies are on record.

Classed as moderate1

The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.

See all 3 studies

Category 2
Skin Irritation · Screening
Classification not possible
Skin Sensitization · Screening
Category 2B
Eye Irritation · Screening