2-hydroxyisobutyric acid is a 2-hydroxy monocarboxylic acid that is isobutyric acid bearing a hydroxy substituent at position 2.
Definition
2-hydroxyisobutyric acid is a 2-hydroxy monocarboxylic acid that is isobutyric acid bearing a hydroxy substituent at position 2. It is a metabolite of methyl tertiary-butyl ether. It has a role as a human xenobiotic metabolite. It is functionally related to an isobutyric acid. It is a conjugate acid of a 2-hydroxyisobutyrate.
Source: PubChem
US FDA substance register · UNII DMW250U2HF · registered name 2-Methyllactic acid · single chemical substance
Cosmetic roles
Safety & regulatory references
Not classified under Korea’s toxic-substance GHS list · existing chemical substance
More data — names, identifiers, properties, test records, literature
Official labels & definitions
JCIA labelling name メチル乳酸: 本品は、次の化学式で表される有機化合物である。
Source: JCIA labelling names (Japan)
Names & identifiers
- CAS No.chemical registry number
- 594-61-6
- EC No.EU chemical inventory number
- 209-848-8
- DTXSIDUS EPA chemical ID
- DTXSID4032954
- DTXCIDUS EPA compound ID
- DTXCID2012954
- IUPAC
- 2-Hydroxy-2-methylpropanoic acid
- Molecular formula
- C4H8O3
- Molecular weight
- 104.105 g/mol
Measured properties
- Appearance
- White crystalline solid, [Sigma-Aldrich MSDS] · Solid
- Boiling point
- 212.00 °C. @ 760.00 mm Hg · 212 °C @760 [mm Hg]
- Melting point
- 82.5 °C
- Colour
- white
- Melting/freezing point
- 82.5 ℃
- Initial boiling point and range
- 212 ℃
- Water solubility
- 1000000 ㎎/ℓ(25℃, est.)
- Vapour density
- (3.6)
- n-Octanol/water partition coefficient (Kow)
- -0.36
- Molecular weight
- 104.105
Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.
Source: PubChem · KOSHA safety data sheets (Korea)
What products actually use it for
What the 1 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Deodorizer1
Source: US EPA CompTox dashboard
Irritation and sensitisation studies
1 skin studies and 1 eye studies are on record.
The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.
See all 2 studies
- Category 6.3A (Category 2)
Skin Irritation · Read Across - Category 6.4A (Category 2A)
Eye Irritation · Read Across
Source: US EPA CompTox dashboard
Linked databases 18
- Australian Industrial Chemicals Inventory (AICIS)
- ChEBI
- ChEMBL
- EU CosIng ingredient list 2
- JCIA labelling names (Japan)
- Korea Cosmetic Association ingredient dictionary
- Korea toxic substances GHS register (NIER)
- KOSHA safety data sheets (Korea)
- MFDS (Korea) cosmetic ingredient register 2
- NIST Chemistry WebBook
- PubChem 2
- UniChem cross-reference IDs
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata
- Wikipedia · Korean · English · Japanese · Chinese