Methyl laurate is a fatty acid methyl ester of lauric acid.
Definition
Methyl laurate is a fatty acid methyl ester of lauric acid. It has a role as a metabolite. It is a fatty acid methyl ester and a dodecanoate ester.
Source: PubChem
US FDA substance register · UNII 8IPS6BI6KW · registered name METHYL LAURATE · single chemical substance
Cosmetic roles
Safety & regulatory references
Not classified under Korea’s toxic-substance GHS list · existing chemical substance
Other restriction: ban substances that deplete the ozone layer
Source: EU CosIng ingredient list
More data — names, identifiers, properties, test records, literature
Names & identifiers
- CAS No.chemical registry number
- 111-82-0
- EC No.EU chemical inventory number
- 203-911-3
- DTXSIDUS EPA chemical ID
- DTXSID5026889
- DTXCIDUS EPA compound ID
- DTXCID206889
- IUPAC
- Methyl dodecanoate
- Molecular formula
- C13H26O2
- Molecular weight
- 214.349 g/mol
Measured properties
- Appearance
- Liquid, Dry Powder, CBI · Water-white liquid, mp = 4.8 deg C, [Hawley] Colorless liquid, [MSDSonline]
- Odour
- FATTY, FLORAL ODOR REMINISCENT OF WINE · OILY, WINEY, FATTY ODOR
- Boiling point
- 267 °C · 148.00 °C. @ 18.00 mm Hg
- Melting point
- 5.2 °C · 5 °C
- Solubility
- Insol in water, miscible with ethyl alcohol, ether, acetone · SOL IN MOST COMMON ORGANIC SOLVENTS
- Density
- 0.8702 @ 20 °C/4 °C · 0.863-0.872
- Melting/freezing point
- 5 ℃
- Initial boiling point and range
- 262 ℃((766 mmHg))
- Flash point
- &, gt, 110 ℃ ((c.c.))
- Upper/lower flammability or explosive limits
- 4.9 / 0.6 %
- Vapour pressure
- 0.00411 ㎜Hg ((25 ℃))
- Relative density
- 0.8702
- n-Octanol/water partition coefficient (Kow)
- 5.41
- Viscosity
- 1.19 cP (80 C)
- Molecular weight
- 214.35
Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.
Source: PubChem · KOSHA safety data sheets (Korea)
What products actually use it for
What the 19 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Softener and conditioner4
- Flavouring and nutrient2
- Fragrance2
- Lubricating agent2
- Emulsifier2
- Waterproofing agent2
- Intermediate2
- Binder1
2 other uses
- Heat transferring agent1
- Solvent1
Source: US EPA CompTox dashboard
Irritation and sensitisation studies
6 skin studies and 3 eye studies are on record.
The studies disagree (the most common conclusion covers 20%), so they do not establish that this ingredient is irritating. These tests are on the raw material itself; irritation at the amount in a finished product is a different question.
See all 9 studies
- Skin corrosion/irritation - Category 2
Skin Irritation · Screening - Category 2
Skin Irritation · Screening - Not likely to be sensitizing
skin sensitisation: in vivo (non-LLNA) · Screening · according to OECD Guideline 406 (Skin Sensitisation) adopted in 1992 according to EU Method B.6 (Skin Sensitisation) adopted in 1996 - Classification not possible
Skin Sensitization · Screening - Severe Irritation
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) adopted in 1992 according to - Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · other guideline: D.O.T. Corrosivity (Skin Irritation on Rabbits,. 49 CFR 173.240) according to OECD Guideline 404 (Acute Dermal Irritation / Corrosion) equivalent or similar to - Category 2B
Eye Irritation · Screening - Studies Indicate No Significant Irritation
eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) according to - Studies Indicate No Significant Irritation
eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) equivalent or similar to
Source: US EPA CompTox dashboard
Related literature
- Biocatalytic Acylation of Menthol with Fatty Acids in Deep Eutectic Solvent as Reaction Environment · 2022
- Pengaruh Proses Pembuatan Terhadap Karakteristik Minyak Kelapa · 2025
- A pseudo-surfactant chemical permeation enhancer to treat otitis media via sustained transtympanic delivery of antibiotics · 2024
- Green Synthesis of Decaglycerol Laurates by Lipase-Catalyzed Transesterification of Methyl Laurate with Decaglycerol · 2019
- Topical Application of Penetration Enhancers to the Skin of Nude Mice: a Histopathological Study · 1989
Linked databases 18
- Australian Industrial Chemicals Inventory (AICIS)
- ChEBI
- ChEMBL
- EU CosIng ingredient list 2
- Korea Cosmetic Association ingredient dictionary
- Korea toxic substances GHS register (NIER)
- KOSHA safety data sheets (Korea)
- MFDS (Korea) cosmetic ingredient register 2
- NIST Chemistry WebBook
- PubChem 2
- Tlooto literature search 2 3 4 5
- UniChem cross-reference IDs
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata
- Wikipedia · English · Chinese