Ingredient Dictionary

METHYL MYRISTATE

Methyl tetradecanoate is a fatty acid methyl ester resulting from the formal condensation of the carboxy group of tetradecanoic acid (myristic acid) with methanol.

Definition

Methyl tetradecanoate is a fatty acid methyl ester resulting from the formal condensation of the carboxy group of tetradecanoic acid (myristic acid) with methanol. It has a role as a flavouring agent, a fragrance and a plant metabolite. It is functionally related to a tetradecanoic acid.

Source: PubChem

US FDA substance register · UNII RG9851783C · registered name METHYL MYRISTATE · single chemical substance

Source: US FDA Unique Ingredient Identifier (UNII)

Cosmetic roles

Makes skin soft and smoothSKIN CONDITIONING - EMOLLIENTKeeps skin in good condition (CosIng catch-all)SKIN CONDITIONING

Safety & regulatory references

Not classified under Korea’s toxic-substance GHS list · existing chemical substance

Source: Korea toxic substances GHS register (NIER)

Reviewed by CIR: Final Report of the Amended Safety Assessment of Myristic Acid and its Salts and Esters as Used in Cosmetics

Source: US Cosmetic Ingredient Review (CIR)

More data — names, identifiers, properties, test records, literature

Names & identifiers

METHYL MYRISTATEINCI메틸미리스테이트Korean label name (MFDS standard)Tetradecanoic acid, methyl esterSynonym

CAS No.chemical registry number: 124-10-7
EC No.EU chemical inventory number: 204-680-1
DTXSIDUS EPA chemical ID: DTXSID5027019
DTXCIDUS EPA compound ID: DTXCID607019

IUPAC: Methyl tetradecanoate
Molecular formula: C15H30O2
Molecular weight: 242.403 g/mol

Measured properties

Appearance: CBI, Liquid · Colorless liquid, mp = 17.8 deg C, [Hawley] Colorless liquid or white solid, mp = 19 deg C, [HSDB] Colorless liquid, mp = 18 deg C, [MSDSonline]
Odour: Honey & orris-like (Iris florentina) odor · FATTY COCONUT, COGNAC ODOR
Boiling point: 295 °C · Boiling point: 155 °C @ 2 mm Hg
Melting point: 19 °C · 18.5 °C
Solubility: Insol in water, miscible in ethyl alcohol, ether, acetone · SOL IN OILS
Density: 0.8671 @ 20 °C · 0.870(15.5 °C)
Colour: colourless
Melting/freezing point: 19 ℃
Initial boiling point and range: 295 ℃
Flash point: &amp, gt, 112 ℃
Vapour pressure: 1 ㎜Hg (at 115 C)
Water solubility: 0.04755 ㎎/ℓ
Vapour density: 8.3
Relative density: 0.9
n-Octanol/water partition coefficient (Kow): 6.41
Viscosity: 2.96 cP (39.9 C)
Molecular weight: 242.42

Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.

Source: PubChem · KOSHA safety data sheets (Korea)

What products actually use it for

What the 10 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.

Flavouring and nutrient2
Fragrance2
Softener and conditioner2
Emulsifier2
Intermediate2

Source: US EPA CompTox dashboard

Irritation and sensitisation studies

1 skin studies and 1 eye studies are on record.

Classed as low1

The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.

See all 2 studies

Not likely to be sensitizing
skin sensitisation: in vivo (non-LLNA) · Screening · according to OECD Guideline 406 (Skin Sensitisation) adopted in 1992 according to EU Method B.6 (Skin Sensitisation) adopted in 1996
Studies Indicate No Significant Irritation
eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) according to