成分辞典

METHYL N-METHYLANTHRANILATE

Methyl N-methylanthranilate is a methyl ester resulting from the formal condensation of the carboxy group of N-methylanthranilic acid with methanol.

定義

Methyl N-methylanthranilate is a methyl ester resulting from the formal condensation of the carboxy group of N-methylanthranilic acid with methanol. It has a role as an animal metabolite, a plant metabolite and a fungal metabolite. It is a methyl ester, a benzoate ester, a substituted aniline and a secondary amino compound. It is functionally related to a N-methylanthranilic acid.

出典: PubChem

米国FDA 物質登録 · UNII 5Z37T562P9 · 登録名 DIMETHYL ANTHRANILATE · 単一の化学物質

出典: 米国FDA 物質識別番号（UNII）

Methyl-N-methylanthranilate is a fragrance ingredient used in various cosmetics, including fine fragrances, shampoos, soaps and other toiletries as well as in non-cosmetic products such as household cleaners and detergents.

化粧品での役割

香料組成に使う物質として登録（香りを出すという意味ではありません）FRAGRANCE

安全性・規制情報

制限: イギリス · 欧州連合 · 国際香料基準（IFRA）

出典: ASEAN 化粧品指令 · EU 化粧品規則 · カナダ禁止・制限成分リスト · IFRA 香料基準 · 韓国食薬処化粧品規制情報 · 英国化粧品規則

ASEAN

Field of application and/or use : (a) Leave-on products (b) Rinse-off products
Maximum authorised concentration in the finished cosmetic product : (a) 0,1 % (b) 0,2 %
Other limitations and requirements : For (a): Not to be used in sunscreen products and products marketed for exposure to natural or artificial UV light. For (a) and (b): — Do not use with nitrosating agents — Maximum nitrosamine content: 50 μg/kg — Keep in nitrite-free containers

カナダ

Maximum Concentration Permitted : 0.1%

유럽

Product Type, body parts : (a) Leave-on products (b) Rinse-off products
Maximum concentration in ready for use preparation : (a) 0,1 % (b) 0,2 %
Other : For (a): Not to be used in sunscreen products and products marketed for exposure to natural or artificial UV light. For (a) and (b): — Do not use with nitrosating agents — Maximum nitrosamine content: 50 μg/kg — Keep in nitrite-free containers

出典: 韓国食薬処化粧品規制情報

韓国の有害物質GHS分類なし · 既存化学物質

出典: 韓国有害物質GHS情報（環境公団）

EU化粧品規則附属書III（制限物質）第323項 · 最大濃度 (a) 0,1 % (b) 0,2 % · 適用 (a) Leave-on products (b) Rinse-off products

出典: EU 制限成分（附属書III）

Restriction Annex III/323 · SCCS opinion: Methyl-N-methylanthranilate Phototoxicity only; Opinion on Methyl-N-methylanthranilate (photo-toxicity only); Scientific Advice on the SCCS Opinion on methyl-N-methylanthranilate (MNM)(SCCS/1455/11).

出典: EU CosIng 成分リスト

詳しい資料 — 表示名・識別番号・物性・試験記録・文献

別名・識別情報

METHYL N-METHYLANTHRANILATEINCIBenzoic acid, 2-(methylamino)-, methyl ester別名METHYL N-METHYL ANTHRANILATE別名

CAS No.化学物質登録番号: 85-91-6
EC No.EU化学物質目録番号: 201-642-6
DTXSID米国EPA化学物質番号: DTXSID1052581
DTXCID米国EPA化合物番号: DTXCID8031154

IUPAC: Methyl 2-(methylamino)benzoate
分子式: C9H11NO2
分子量: 165.192 g/mol

測定された物性

性状: Colorless or pale yellow liquid with an odor of grapes, [Hawley] Pale-yellow liquid with a slightly blue fluorescence or solid, Odor like orange peels, mp = 18.5-19.5 deg C, [HSDB] · Liquid
臭い: ORANGE & MANDARIN-PEEL-LIKE ODOR
沸点: 256 °C @ 760 MM HG · 255.00 to 256.00 °C. @ 760.00 mm Hg
融点: 18.5-19.5 °C · 19 °C
溶解性: INSOL IN WATER, SOL IN ALCOHOL, ETHER · SOL IN MOST COMMON ORGANIC SOLVENTS
密度: 1.120 @ 15 °C · 1.124-1.132
融点・凝固点: 17 ℃(18.5~19.5℃(HSDB))
初留点および沸点範囲: 258 ℃(256℃(HSDB))
比重: 1.120 (15℃)
分子量: 165.19

物質そのものを測定した値です。安全保健公団（KOSHA）の資料はSDS作成・確認の参考用で、原料商品の規格ではありません。

出典: PubChem · 韓国安全保健公団 SDS

製品が実際に使っている用途

米国EPAにこの成分を届け出た製品59件の用途です。化粧品以外の製品も含まれるため、上の数行がこの成分の主な使い道といえます。

Fragrance56
Flavouring and nutrient3

出典: 米国EPA CompTox

刺激・感作試験の記録

皮膚試験4件・眼試験2件の記録があります。

低いと分類7件

試験の結論はおおむね一致しています（100%）。原料そのものを試験した記録で、完成品に含まれる濃度での刺激性とは異なります。

試験6件をすべて見る

Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · other guideline: as mentioned below according to
Not likely to be sensitizing
skin sensitisation: in vivo (non-LLNA) · Screening · according to other guideline: as mentioned below
Category 6.3A (Category 2)
Skin Irritation · Read Across
Not likely to be sensitizing
skin sensitisation · Screening · according to other guideline: as mentioned below
Category 6.4A (Category 2A)
Eye Irritation · Read Across
Severe Irritation
eye irritation: in vivo · Screening · other guideline: as mentioned below equivalent or similar to