Methyl nicotinate is a member of pyridines and an aromatic carboxylic acid.
How much products actually contain
No product states its amount yet.
Of the products containing it, 20 list it before the 1% line and 17 after it (usually 1% or less).
Products using this ingredient
12 of 37 confirmed · likeliest to carry enough first · See all 37
Melt CosmeticsMelt Cosmetics Hot Shot Matte Lip Plumper
r.e.m. beautyr.e.m. beauty r.e.m. beauty x Wicked: For Good tulip field lip stain
r.e.m. beautyr.e.m. beauty r.e.m. beauty x Wicked: For Good Poppy Plumping Lip Gloss
M·A·CM·A·C Squirt Plumping Gloss Stick - Amped
M·A·CM·A·C Squirt Plumping Gloss Stick - Clear
M·A·CM·A·C Squirt Plumping Gloss Stick - Hazard
M·A·CM·A·C Squirt Plumping Gloss Stick - Heat Sensor
M·A·CM·A·C Squirt Plumping Gloss Stick - Jet
M·A·CM·A·C Squirt Plumping Gloss Stick - Lava Sparks
M·A·CM·A·C Squirt Plumping Gloss Stick - Like Squirt
M·A·CM·A·C Squirt Plumping Gloss Stick - Lower Cut
M·A·CM·A·C Squirt Plumping Gloss Stick - Nova
Definition
Methyl nicotinate is a member of pyridines and an aromatic carboxylic acid.
Source: PubChem
US FDA substance register · UNII 7B1AVU9DJN · registered name Methyl Nicotinate · single chemical substance
Cosmetic roles
More data — names, identifiers, properties, test records, literature
Official labels & definitions
JCIA labelling name ニコチン酸メチル: 本品は、ナイアシン(*)のメチルエステルであり、次の化学式で表される。
Source: JCIA labelling names (Japan)
Names & identifiers
- CAS No.chemical registry number
- 93-60-7
- EC No.EU chemical inventory number
- 202-261-8
- DTXSIDUS EPA chemical ID
- DTXSID7044471
- DTXCIDUS EPA compound ID
- DTXCID5024471
- IUPAC
- Methyl pyridine-3-carboxylate
- Molecular formula
- C7H7NO2
- Molecular weight
- 137.138 g/mol
Measured properties
- Appearance
- Solid, [Merck Index] · Solid
- Boiling point
- 209 · 209.00 °C. @ 760.00 mm Hg
- Melting point
- 38-43 · 38 °C
- Solubility
- Soluble · 47.6 mg/mL at 20 °C
Values measured on the substance itself, not a specification for a commercial raw material.
Source: PubChem
What products actually use it for
What the 10 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Humectant4
- Flavouring and nutrient2
- Fragrance2
- Softener and conditioner1
- Pharmaceutical (EPA)1
Source: US EPA CompTox dashboard
Irritation and sensitisation studies
4 skin studies and 1 eye studies are on record.
The studies disagree (the most common conclusion covers 50%), so they do not establish that this ingredient is irritating. These tests are on the raw material itself; irritation at the amount in a finished product is a different question.
See all 5 studies
- Category 6.5B (Category 1)
Skin Sensitization · Read Across - Not likely to be sensitizing
skin sensitisation · Screening · according to other guideline: As mentioned below - Severe Irritation
skin irritation: in vivo · Screening · other guideline: as mentioned below according to - SkinSens1
Skin Sensitization · QSAR Predicted - Category 6.4A (Category 2A)
Eye Irritation · Read Across
Source: US EPA CompTox dashboard
Related literature
- Topical Application of Methyl Nicotinate Solution Enhances Peripheral Blood Collection. · 2022
- Skin blood flow response to topically applied methyl nicotinate: Possible mechanisms · 2019
- Combination of Comfrey Root Extract Plus Methyl Nicotinate in Patients with Conditions of Acute Upper or Low Back Pain: A Multicentre Randomised Controlled Trial · 2012
- Establishing a Minimal Erythema Concentration of Methyl Nicotinate for Optimum Evaluation of Anti-Inflammatories · 2006
- Correlation between percutaneous penetration of methyl nicotinate and sensitive skin, using laser Doppler imaging · 1998
Linked databases 18
- Australian Industrial Chemicals Inventory (AICIS)
- ChEBI
- ChEMBL
- China inventory of existing ingredients (IECIC)
- EU CosIng ingredient list 2
- JCIA labelling names (Japan)
- Korea Cosmetic Association ingredient dictionary
- MFDS (Korea) cosmetic ingredient register 2
- NIST Chemistry WebBook
- PubChem 2
- Tlooto literature search 2 3 4 5
- UniChem cross-reference IDs
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata
- Wikipedia · English · Chinese