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成分辞典

成分辞典

METHYL THIOGLYCOLATE

Methyl Thioglycolate is the ester of methyl alcohol and Thioglycolic Acid.

分子構造

定義

米国FDA 物質登録 · UNII O1608LA9EL · 登録名 METHYL THIOGLYCOLATE · 単一の化学物質

出典: 米国FDA 物質識別番号(UNII)

Methyl Thioglycolate is the ester of methyl alcohol and Thioglycolic Acid. It conforms to the formula:

化粧品での役割

髪をカールまたはストレートにするHAIR WAVING OR STRAIGHTENING

安全性・規制情報

制限
中国

出典: 韓国食薬処 化粧品規制情報

アルゼンチン · ブラジル

  • Field of application and/or use : Products for straightening or waving hair: 1. General use 2. Professional use
  • Maximum concentration permitted at final product : 1. 8% ready to use pH 6 to 9,5 2.11% ready to use pH 6 to 9.5 The percentages are calculated as thioglycolic acid
  • Other limitations and requirements : 1) and 2) In the USAGE must consist obligatorily the following information: - May cause sensitization by skin contact. - Avoid contact with eyes. - In case of contact with eyes, rinse immediately and thoroughly with water and consult a doctor. - Wear suitable gloves
  • Use conditions and warnings that must appear on the label : 1) and 2) Contains thioglycolate Follow the instructions Keep out of reach of children. For professional use only (if applicable)

ASEAN

  • Field of application and/or use : Hair waving or straightening products: 1. General use 2. Professional use
  • Maximum authorised concentration in the finished cosmetic product : 1. 8% ready for use at pH 6-9.5 2. 11% ready for use at pH 6-9.5 Percentages calculated as thioglycolic acid.
  • Other limitations and requirements : The directions for use drawn up in the national or official language(s) must obligatorily incorporate the following sentences: • May cause sensitisation in the event of skin contact. • Avoid contact with eyes. • In the event of contact with eyes, rinse immediately with plenty of water and seek medical advice. • Wear suitable gloves.
  • Conditions of use and warning which must be printed on the labels : • Contains thioglycolate. • Follow the instructions. • Keep out of reach of children. • For professional use only.

欧州連合

  • Product Type, body parts : Hair waving or straightening products
  • Maximum concentration in ready for use preparation : (a) 8% (b) 11% The abovementioned percentages are calculated as thioglycollic acid
  • Other : (a) General use ready for use pH 6 to 9.5 (b) Professional use ready for use pH 6 to 9.5
  • Wording of conditions of use and warnings : Conditions of use: (a) (b) May cause sensitization in the event of skin contact Avoid contact with eyes In the event of contact with eyes, rinse immediately with plenty of water and seek medical advice Wear suitable gloves Warnings: Contains thioglycolate Follow the instructions Keep out of reach of children (b) For professional use only

出典: 韓国食薬処 化粧品規制情報

韓国の有害物質GHS分類: 危険 · H301 (区分3)

出典: 韓国 有害物質GHS情報(環境公団)

Restriction III/2b

出典: EU CosIng 成分リスト

Reviewed by CIR: Final Amended Report on the Safety Assessment of Ammonium Thioglycolate, Butyl Thioglycolate, Calcium Thioglycolate, Ethanolamine Thioglycolate, Ethyl Thioglycolate, Glyceryl Thioglycolate, Isooctyl Thioglycolate, Isopropyl Thioglycolate, Magnesium Thioglycolate, Methyl Thioglycolate, Potassium Thioglycolate, Sodium Thioglycolate, and Thioglycolic Acid

出典: 米国CIR 安全性評価

詳しい資料 — 表示名・識別番号・物性・試験記録・文献

別名・識別情報

METHYL THIOGLYCOLATEINCI메틸티오글라이콜레이트韓国の表示名(食薬処標準名)Acetic acid, mercapto-, methyl ester別名
CAS No.化学物質登録番号
2365-48-2
EC No.EU化学物質目録番号
219-121-7
DTXSID米国EPA化学物質番号
DTXSID0033673
DTXCID米国EPA化合物番号
DTXCID8013673
IUPAC
Methyl sulfanylacetate
分子式
C3H6O2S
分子量
106.14 g/mol

測定された物性

性状
Colorless liquid with a stench, [MSDSonline] · 液体
沸点
148 °C
解離定数
pKa= 8.08 @ 25 °C
色
無色
融点・凝固点
-52.4 ℃
初留点および沸点範囲
148 ℃
蒸気圧
3 ㎜Hg
溶解度
60070 ㎎/ℓ
蒸気密度
3.6641353123921303
n-オクタノール/水分配係数(Kow)
0.32
自然発火温度
56 ℃
分子量
106.15

物質そのものを測定した値です。安全保健公団(KOSHA)の資料はSDS作成・確認の参考用で、原料商品の規格ではありません。

出典: PubChem · 韓国安全保健公団 SDS

製品が実際に使っている用途

米国EPAにこの成分を届け出た製品1件の用途です。化粧品以外の製品も含まれるため、上の数行がこの成分の主な使い道といえます。

  • Hair waving or straightening (EPA)1

出典: 米国EPA CompTox

刺激・感作試験の記録

皮膚試験3件・眼試験1件の記録があります。

中程度と分類1件

試験の結論はおおむね一致しています(100%)。 原料そのものを試験した記録で、完成品に含まれる濃度での刺激性とは異なります。

試験4件をすべて見る
  • SkinSens1
    Skin Sensitization · QSAR Predicted
  • Category 6.5B (Category 1)
    Skin Sensitization · Read Across
  • Category 6.3A (Category 2)
    Skin Irritation · Read Across
  • Category 6.4A (Category 2A)
    Eye Irritation · Read Across

出典: 米国EPA CompTox

関連文献

連携データベース 17