这种成分是什么?

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成分词典

METHYLCHLOROISOTHIAZOLINONE

Chloromethylisothiazolinone is a 1,2-thiazole that is 4-isothiazolin-3-one bearing a methyl group on the nitrogen atom and a chlorine at C-5.

韩国限量: 0.0015%

产品中实际含有多少

暂无产品标示该成分含量。

含该成分的产品中，4 款将其列在 1% 线之前，64 款列在之后（通常不超过 1%）。

含有此成分的产品

已确认 68 款中的 12 款 · 按含量充足程度排序 · 查看全部 68 款

定义

美国FDA 物质登记 · UNII DEL7T5QRPN · 登记名称 METHYLCHLOROISOTHIAZOLINONE · 单一化学物质

来源: 美国FDA 物质识别码（UNII）

Chloromethylisothiazolinone is a 1,2-thiazole that is 4-isothiazolin-3-one bearing a methyl group on the nitrogen atom and a chlorine at C-5. It is a powerful biocide and preservative and is the major active ingredient in the commercial product KathonTM. It has a role as an antimicrobial agent, a xenobiotic and an environmental contaminant. It is an organochlorine compound and a member of 1,2-thiazoles. It is functionally related to a methylisothiazolinone.

来源: PubChem

Methylchloroisothiazolinone is the heterocyclic organic compound that conforms to the formula:

化妆品中的作用

防止产品中微生物滋生PRESERVATIVE

安全与法规参考

限用: 韩国

来源: 韩国食药处化妆品法规信息

阿根廷 · 巴西

Maximum concentration permitted at final product : 0.0015% (a mixture in proportions of 3: 1 5-Chloro-2-methyl- isothiazol-3 (2H) -one and 2- Methylisothiazol-3 (2H) -one)

东盟

Maximum authorised concentration in the finished cosmetic product : 0.0015 % (of a mixture in the ratio 3:1 of 5-chloro- 2-methylisothiazol 3(2H)-one and 2-methylisothiazol-3(2H)-one)
Other limitations and requirements : Rinse-off products

加拿大

Conditions of Use by product type : (a) Not permitted in leave-on products. (b) Rinse-off products Note: If MI is present in a formulation with Methylisothiazolinone / Methylchloroisothiazolinone (MI/MCI) in combination, the cumulative, total concentration of MI and MI/MCI may not exceed 0.0015%.
Maximum Concentration Permitted : b) 0.0015%

中国

最大配合量 : 0.0015%

欧盟

Product Type, body parts : rinse-off products
Maximum concentration in ready for use preparation : 0.0015% (of a mixture in the ratio 3:1 of 5-Chloro-2-methyl-isothiazol-3(2H)-one and 2-Methylisothiazol-3(2H)-one

来源: 韩国食药处化妆品法规信息

韩国有毒物质 GHS 分类: 危险 · H400 (第1类) · H410 (第1类) · H314 (第1B类) · 另有 4 项

来源: 韩国有毒物质 GHS 信息（环境公团）

Restriction V/39

来源: 欧盟 CosIng 成分清单

Reviewed by CIR: Final Report on the Safety Assessment of Methylisothiazolinone and Methylchloroisothiazolinone

来源: 美国CIR 安全性评估

Reviewed by CIR: Ammended Safety Assessment of Methylisothiazolinone and Methylchloroisothiazolinone as Used in Cosmetics

来源: 美国CIR 安全性评估

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