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Ingredient Dictionary

METHYLENE BIS-BENZOTRIAZOLYL TETRAMETHYLBUTYLPHENOL

Bisoctrizole is a diarylmethane.

Korean limit
10%
Molecular structure

How much products actually contain

No product states its amount yet.

Of the products containing it, 135 list it before the 1% line and 3 after it (usually 1% or less).

Products using this ingredient

12 of 138 confirmed · likeliest to carry enough first · See all 138

Definition

Bisoctrizole is a diarylmethane.

Source: PubChem

US FDA substance register · UNII 8NT850T0YS · registered name BISOCTRIZOLE · single chemical substance

Source: US FDA Unique Ingredient Identifier (UNII)

Methylene Bis-Benzotriazolyl Tetramethylbutylphenol is the heterocyclic compound that conforms to the formula:

Cosmetic roles

Protects colour and scent from lightLIGHT STABILIZERFilters UV to protect skin (sunscreen active)UV FILTER

Safety & regulatory references

Allowed UV filter
United Kingdom

Source: ASEAN Cosmetic Directive · EU Cosmetics Regulation · Taiwan FDA cosmetic ingredients · UK cosmetics regulations (OPSS)

Argentina · Brazil

  • Maximum concentration permitted at final product : 10%

ASEAN

  • Maximum authorised concentration in the finished cosmetic product : 10%

Taiwan · China · South Korea

  • Maximum concentration : 10%

Japan

  • Maximum amount per 100 g (Cosmetics not used for mucosa and to be washed away) : 10.0 g
  • Maximum amount per 100 g (Cosmetics not used for mucosa and not to be washed away) : 10.0 g

European Union

  • Maximum concentration in ready for use preparation : 10 %(*) (*) In case of combined use of Methylene Bis-Benzotriazolyl Tetramethylbutylphenol and Methylene Bis-Benzotriazolyl Tetramethylbutylphenol (nano), the sum shall not exceed the limit given in column g.’.
  • Other : Not to be used in applications that may lead to exposure of the end user's lungs by inhalation. Only nanomaterials having the following characteristics are allowed: — Purity ≥ 98,5 %, with 2,2′-methylene-bis- (6(2H-benzotriazol-2-yl)-4-(isooctyl)phenol) isomer fraction not exceeding 1,5 %; — Solubility < 5 ng/L in water at 25 °C; — Partition coefficient (Log Pow): 12,7 at 25 °C; — Uncoated; — Median particle size D50 (50 % of the number below this diameter): ≥ 120 nm of mass distribution and/or ≥ 60 nm of number size distribution.
  • Maximum concentration in ready for use preparation : 10%

Source: MFDS (Korea) cosmetic regulatory information

Not classified under Korea’s toxic-substance GHS list · existing chemical substance

Source: Korea toxic substances GHS register (NIER)

EU Cosmetics Regulation, Annex VI (allowed UV filters), entry 23a · maximum concentration 10 %(*) (*) In case of combined use of Methylene Bis-Benzotriazolyl Tetramethylbutylphenol and Methylene Bis-Benzotriazolyl Tetramethylbutylphenol (nano), the sum shall not exceed the limit given in column g.’.

Source: EU allowed UV filters (Annex VI)

EU Cosmetics Regulation, Annex VI (allowed UV filters), entry 23 · maximum concentration 10%

Source: EU allowed UV filters (Annex VI)

Restriction VI/23 · Other restriction: ban substances that deplete the ozone layer · SCCS opinion: Opinion on 2,2’-Methylene-bis-(6-(2H-benzotriazol-2-yl)-4-(1,1,3,3-tetramethylbutyl)phenol) (nano form); Opinion on 2,2’-Methylene-bis-(6-(2H-benzotriazol-2-yl)-4-(1,1,3,3-tetramethylbutyl)phenol) nano form (S79) Revision of 23 July 2013; Opinion on 2,2'-Methylene-bis(6-(2H-benzotriazol-2-yl)-4-(1,1,3,3-tetramethylbutyl)phenol)

Source: EU CosIng ingredient list

More data — names, identifiers, properties, test records, literature

Official labels & definitions

JCIA labelling name メチレンビスベンゾトリアゾリルテトラメチルブチルフェノール: 本品は、次の化学式で表される複素環式化合物である。

Source: JCIA labelling names (Japan)

Names & identifiers

METHYLENE BIS-BENZOTRIAZOLYL TETRAMETHYLBUTYLPHENOLINCI메칠렌비스-벤조트리아졸릴테트라메칠부틸페놀Korean label name (MFDS standard)Phenol, 2,2'-methylenebis[6-(2H-benzotriazol-2-yl]-4-(1,1,3,3-tetramethylbutyl)-SynonymメチレンビスベンゾトリアゾリルテトラメチルブチルフェノールJapanese labelling name
CAS No.chemical registry number
103597-45-1
EC No.EU chemical inventory number
403-800-1
DTXSIDUS EPA chemical ID
DTXSID2046703
DTXCIDUS EPA compound ID
DTXCID0026703
IUPAC
2,2'-Methylenebis[6-(2H-1,2,3-benzotriazol-2-yl)-4-(2,4,4-trimethylpentan-2-yl)phenol]
Molecular formula
C41H50N6O2
Molecular weight
658.891 g/mol

Measured properties

Appearance
Other Solid, Dry Powder, Large Crystals
Melting point
195
Solubility
< 5 ng/L at 25 °C

Values measured on the substance itself, not a specification for a commercial raw material.

Source: PubChem

What products actually use it for

What the 23 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.

  • UV stabilizer20
  • Stabilizing agent2
  • Photosensitive agent1

Source: US EPA CompTox dashboard

Irritation and sensitisation studies

2 skin studies and 1 eye studies are on record.

Classed as low2

The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.

See all 3 studies
  • Not likely to be sensitizing
    skin sensitisation: in vivo (non-LLNA) · Screening · according to OECD Guideline 406 (Skin Sensitisation)
  • Not likely to be sensitizing
    skin sensitisation · Screening · equivalent or similar to other guideline: not specified
  • Studies Indicate No Significant Irritation
    eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) according to

Source: US EPA CompTox dashboard

Related literature

Linked databases 25

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