Is there safety information?

전반적으로 안전한 원료임

Are there usage precautions?

pH조절제, 계면활성제 보조, 제형안정화 (추천 피부타입: 모든피부타입)

Ingredient Dictionary

METHYLGLUCAMINE

Q: Is there safety information?

전반적으로 안전한 원료임

N-methylglucamine is a hexosamine that is D-glucitol in which the hydroxy group at position 1 is substituted by the nitrogen of a methylamino group.

METHYLGLUCAMINE Molecular structure — Molecular structure

How much products actually contain

No product states its amount yet.

Of the products containing it, 7 list it before the 1% line and 18 after it (usually 1% or less).

Products using this ingredient

12 of 25 confirmed · likeliest to carry enough first · See all 25

Definition

N-methylglucamine is a hexosamine that is D-glucitol in which the hydroxy group at position 1 is substituted by the nitrogen of a methylamino group. A crystalline base, it is used in preparing salts of certain acids for use as diagnostic radiopaque media, while its antimonate is used as an antiprotozoal in the treatment of leishmaniasis. It is a hexosamine and a secondary amino compound.

Source: PubChem

US FDA substance register · UNII 6HG8UB2MUY · registered name Meglumine · single chemical substance

Source: US FDA Unique Ingredient Identifier (UNII)

Cosmetic roles

Softens hairHAIR CONDITIONING

Safety & regulatory references

Not classified under Korea’s toxic-substance GHS list · existing chemical substance

Source: Korea toxic substances GHS register (NIER)

More data — names, identifiers, properties, test records, literature

Official labels & definitions

JCIA labelling name メチルグルカミン: 本品は、次の化学式で表される有機化合物である。

Source: JCIA labelling names (Japan)

Names & identifiers

METHYLGLUCAMINEINCI메틸글루카민Korean label name (MFDS standard)D-Glucitol, 1-deoxy-1-(methylamino)-SynonymメチルグルカミンJapanese labelling name

CAS No.chemical registry number: 6284-40-8
EC No.EU chemical inventory number: 228-506-9
DTXSIDUS EPA chemical ID: DTXSID0023244
DTXCIDUS EPA compound ID: DTXCID503244

IUPAC: 1-Deoxy-1-(methylamino)-D-glucitol
Molecular formula: C7H17NO5
Molecular weight: 195.215 g/mol

Measured properties

Appearance: Dry Powder, Liquid · solid
Dissociation constant: 9.6
Colour: white
Melting/freezing point: 10~50 ℃
Initial boiling point and range: 210 ℃(at 1013hPa)
Vapour pressure: 0.0000000134 ㎜Hg (est.)
Water solubility: 500000 ㎎/ℓ
Relative density: 1.1-1.2 (g/cm3 at 50C)
n-Octanol/water partition coefficient (Kow): -3.15
Viscosity: (40mPas at 40C)
Molecular weight: 195.22

Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.

Source: PubChem · KOSHA safety data sheets (Korea)

What products actually use it for

What the 4 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.

Surfactant (surface active agent)1
Reducing agent1
Softener and conditioner1
Intermediate1

Source: US EPA CompTox dashboard

Irritation and sensitisation studies

2 skin studies and 0 eye studies are on record.

Classed as low2

The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.

See all 2 studies

Not likely to be sensitizing
skin sensitisation: in vivo (LLNA) · Screening · according to OECD Guideline 429 (Skin Sensitisation: Local Lymph Node Assay) according to EU Method B.42 (Skin Sensitisation: Local Lymph Node Assay) according to EPA OPPTS 870.2600 (Skin Sensitisation)
Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) 1987 according to