メチルパラベン

Methylparaben is the ester of methyl alcohol and p-hydroxybenzoic acid. It conforms to the formula:

Methylparaben is a 4-hydroxybenzoate ester resulting from the formal condensation of the carboxy group of 4-hydroxybenzoic acid with methanol. It is the most frequently used antimicrobial preservative in cosmetics. It occurs naturally in several fruits, particularly in blueberries. It has a role as an antifungal agent, a neuroprotective agent, an antimicrobial food preservative and a plant metabolite.

出典: PubChem

米国FDA 物質登録 · UNII A2I8C7HI9T · 登録名 Methylparaben · 単一の化学物質

出典: 米国FDA 物質識別番号（UNII）

制限

韓国 · 中国

出典: 韓国食薬処 化粧品規制情報

アルゼンチン · ブラジル

• Maximum concentration permitted at final product : (a) 0,4% (expresso como ácido) para cada substância considerada em forma individual. (b) 0,8% (expresso como ácido) para a soma das concentrações individuais de ácido 4-p-hidroxibenzóico, seus ésteres de metil e etil e seus sais contidos no produto.
• Other limitations and requirements : Prohibit: isopropylparaben, isobutylparaben, fenylparaben, benzylparaben, pentylparaben.

ASEAN

• Maximum authorised concentration in the finished cosmetic product : 0.4% (as acid) for single ester 0.8% (as acid) for mixtures of esters

台湾

• 倘前述三國家地區政府管理有差異時，則採其中限量規定方式最安全者。
• ※ 本表所稱之口腔製劑，包含非藥用牙膏、漱口水類及美白牙齒類等化粧品。
• 用途 : 防腐
• 最大配合量 : (a) 0.4% (以 acid 計，單獨使用)
• (b) 0.8% (以 acid 計，混合使用)
• (a) 0.4%
• (b) 0.8%

日本

• 100gあたりの最大配合量(Maximum amount of ingredient per 100 g) : 1.0 as total(合計量として1.0)

欧州連合

• Maximum concentration in ready for use preparation : 0,4% (as acid) for single ester 0,8% (as acid) for mixtures of esters

韓国の有害物質GHS分類なし · 既存化学物質

出典: 韓国 有害物質GHS情報（環境公団）

Restriction V/12 · Other restriction: ban substances that deplete the ozone layer · SCCS opinion: Extended Opinion on the Safety Evaluation of Parabens; Opinion concerning Restrictions on Materials listed in annex VI of Directive 76/768/EEC on Cosmetic Products; Opinion on Parabens; Opinion on Parabens updated request for a scientific opinion on 'propyl-and butylparaben'; Opinion on Parabens, underarm cosmetics and breast cancer

出典: EU CosIng 成分リスト

Reviewed by CIR: Final Amended Report on the Safety Assessment of Methylparaben, Ethylparaben, Propylparaben, Isopropylparaben, Butylparaben, Isobutylparaben and Benzylparaben as used in cosmetic products

出典: 米国CIR 安全性評価

Reviewed by CIR: Amended Safety Assessment of Parabens as Used in Cosmetics

出典: 米国CIR 安全性評価

Reviewed by CIR: Final Report on the Safety Assessment of Methylparaben, Ethylparaben, Propylparaben, and Butylparaben

出典: 米国CIR 安全性評価