定义
美国FDA 物质登记 · UNII 722CLJ6H6K · 登记名称 2-Methyl-4'-(methylthio)-2-morpholinopropiophenone · 单一化学物质
Methylthiophenyl Morpholino Isobutanone is the organic compound that conforms to the formula:
化妆品中的作用
使粉体黏合成形BINDING
安全与法规参考
- 禁用
- 东盟 · 欧盟 · 英国
来源: 东盟化妆品指令 · 欧盟化妆品法规 · 韩国食药处 化妆品法规信息 · 英国化妆品法规
未列入韩国有毒物质 GHS 分类 · 现有化学物质
欧盟化妆品法规 附录II（禁用物质） 第1592项
来源: 欧盟禁用成分（附录II）
Restriction II/1592
来源: 欧盟 CosIng 成分清单
详细资料——标示名称、识别编号、物性、试验记录、文献
别名和识别信息
METHYLTHIOPHENYL MORPHOLINO ISOBUTANONEINCI1-Propanone, 2-methyl-1-[4-(methylthio)phenyl]-2-(4-morpholinyl)-同义名
- CAS No.化学物质登记号
- 71868-10-5
- EC No.欧盟化学品目录编号
- 400-600-6
- DTXSID美国EPA化学品编号
- DTXSID8038857
- DTXCID美国EPA化合物编号
- DTXCID6018857
- IUPAC
- 2-Methyl-1-[4-(methylsulfanyl)phenyl]-2-(morpholin-4-yl)propan-1-one
- 分子式
- C15H21NO2S
- 分子量
- 279.4 g/mol
产品实际使用的用途
这是向美国 EPA 申报含该成分的 18 款产品的用途。其中包括化妆品以外的产品，排在前几行的即为该成分的主要用途。
- Photosensitizers12
- Processing aids not otherwise specified3
- Photosensitive agent2
- Binder1
来源: 美国EPA CompTox
刺激与致敏试验记录
记录有皮肤试验 8 项、眼部试验 4 项。
归类为低7 项
试验结论基本一致（100%）。 这是对原料本身的试验记录，与成品中所含浓度下的刺激性不同。
查看全部 12 项试验
- Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) according to - Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · other guideline: OECD 404 according to - Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · other guideline: US EPA s 163.81-5 "Primary dermal irritation study". Federal Register, Vol. 43, No. 163, August 22, 1978. according to - Classification not possible
Skin Irritation · Screening - Not likely to be sensitizing
skin sensitisation · Screening · according to other guideline: 79/831/EEC, Annex V, part B.417 (maximisation test) - Not likely to be sensitizing
skin sensitisation · Screening · according to other guideline: 79/831/EEC, Annex V, part B. 417 (maximisation test) - Not likely to be sensitizing
skin sensitisation: in vivo (non-LLNA) · Screening · equivalent or similar to OECD Guideline 406 (Skin Sensitisation) modified - Classification not possible
Skin Sensitization · Screening - Studies Indicate No Significant Irritation
eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) according to - Studies Indicate No Significant Irritation
eye irritation: in vivo · Screening · other guideline: OECD 405 according to - Classification not possible
Eye Irritation · Screening - Studies Indicate No Significant Irritation
eye irritation: in vivo · Screening · other guideline: EPA, s 163.81-4 "Primary eye irritation study". Federal Register, Vol. 43, No. 163, August 22, 1978. according to
来源: 美国EPA CompTox