Ligroine. A complex combination of hydrocarbons obtained by the fractional distillation of petroleum.
Definition
US FDA substance register · UNII 5OQ4BMR99T · registered name LIGROIN · biological origin (no fixed structure)
Ligroine. A complex combination of hydrocarbons obtained by the fractional distillation of petroleum. This fraction boils in a range of approximately 20[0]C to 135[0]C (58[0]F to 275[0]F)
Cosmetic roles
Safety & regulatory references
Not classified under Korea’s toxic-substance GHS list · existing chemical substance
More data — names, identifiers, properties, test records, literature
Official labels & definitions
JCIA labelling name ミネラルスピリッツ: 本品は、石油を１５９～２０４℃で蒸留して得られる炭化水素である。
Source: JCIA labelling names (Japan)
Names & identifiers
- CAS No.chemical registry number
- 64475-85-0
- CAS No.chemical registry number
- 8032-32-4
- EC No.EU chemical inventory number
- 232-453-7
- DTXSIDUS EPA chemical ID
- DTXSID5027699
Measured properties
- Appearance
- liquid
- Colour
- colourless
- Melting/freezing point
- &, lt, -73 ℃
- Initial boiling point and range
- 25~80 ℃
- Flash point
- -26 ℃
- Upper/lower flammability or explosive limits
- 5.9 / 1.1 %
- Vapour pressure
- (&, lt, = 240 kPa, 37.8 °C)
- Vapour density
- 2.5-4.3
- Relative density
- 0.62~0.88 (15 °C)
- n-Octanol/water partition coefficient (Kow)
- 2.1~6 (est.)
- Auto-ignition temperature
- (&, gt, 200 ℃, ca. 101.325 kPa)
- Viscosity
- &, lt, 1 ㎡/s (37.8 °C)
- Molecular weight
- 195.33948
Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.
Source: KOSHA safety data sheets (Korea)
Irritation and sensitisation studies
5 skin studies and 1 eye studies are on record.
The studies disagree (the most common conclusion covers 6%), so they do not establish that this ingredient is irritating. These tests are on the raw material itself; irritation at the amount in a finished product is a different question.
See all 6 studies
- Ambiguous
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) equivalent or similar to - Not likely to be sensitizing
skin sensitisation: in vivo (non-LLNA) · Screening · equivalent or similar to OECD Guideline 406 (Skin Sensitisation) - Ambiguous
skin corrosion: in vitro / ex vivo · Screening · other guideline: OECD Guideline 431 (incorporated into OECD 435) equivalent or similar to - Ambiguous
skin irritation: in vivo · Screening · other guideline: As detailed in study report according to - Severe Irritation
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) according to - Studies Indicate No Significant Irritation
eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) equivalent or similar to
Source: US EPA CompTox dashboard
Related literature
- Not All Rashes Are Allergic: Keratoderma Blennorrhagicum-Like Rash Masquerading as Contact Dermatitis · 2018
- Stuck in a Bind: A Case Report of Occupational Tar/Asphalt Burn · 2026
- Health hazard evaluation of art materials used at the Cooper Union School of Art, New York · 2017
- Dermal Versus Total Uptake of Benzene from Mineral Spirits Solvent During Parts Washing · 2014
- Authors’ response to Comments on Petty et al. (2011), “A Quantitative Method for Estimating Dermal Benzene Absorption from Benzene-Containing Hydrocarbon Liquids,” IJOEH, 17:287–300 by Pamela R.D. Williams, Jennifer Sahmel, Annette L. Bunge, Jeffrey Knutsen, and John Spencer · 2013
Linked databases 15
- Australian Industrial Chemicals Inventory (AICIS)
- China inventory of existing ingredients (IECIC)
- EU CosIng ingredient list 2
- JCIA labelling names (Japan)
- Korea Cosmetic Association ingredient dictionary
- Korea toxic substances GHS register (NIER)
- KOSHA safety data sheets (Korea)
- MFDS (Korea) cosmetic ingredient register 2
- Tlooto literature search 2 3 4 5
- US EPA CompTox dashboard
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata
- Wikipedia · Korean · English · Japanese · Chinese