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成分词典

成分词典

MUSK XYLENE

Musk xylene is a C-nitro compound that is m-xylene bearing three nitro substituents at positions 2, 4 and 6 as well as a tert-butyl group at position 5.

分子结构

定义

Musk xylene is a C-nitro compound that is m-xylene bearing three nitro substituents at positions 2, 4 and 6 as well as a tert-butyl group at position 5. It has a role as a fragrance, a carcinogenic agent and an explosive. It is functionally related to a m-xylene and a 1,3,5-trinitrobenzene.

来源: PubChem

美国FDA 物质登记 · UNII 1ZAO16GU5K · 登记名称 MUSK XYLENE · 单一化学物质

来源: 美国FDA 物质识别码(UNII)

化妆品中的作用

为产品增添香味PERFUMING登记为香料组成物质(并非表示其增香)FRAGRANCE

安全与法规参考

禁用
国际香料标准(IFRA)
限用
韩国 · 英国 · 中国

来源: IFRA 香料标准 · 东盟化妆品指令 · 欧盟化妆品法规 · 韩国食药处 化妆品法规信息 · 英国化妆品法规

阿根廷 · 巴西

  • Field of application and/or use : All products, except for products for oral hygiene
  • Maximum concentration permitted at final product : a) 1% in fine fragrances. b) 0,4% in eau de toilette c) 0.03% other products

东盟

  • Field of application and/or use : All cosmetic products, with the exception of oral care products
  • Maximum authorised concentration in the finished cosmetic product : (a) 1.0 % in fine fragrance (b) 0.4 % in eau de toilette (c) 0.03 % in other products

欧盟

  • Product Type, body parts : All cosmetic products, with the exception of oral products
  • Maximum concentration in ready for use preparation : (a) 1.0% in fine fragrance (b) 0.4% in eau de toilette (c) 0.03% in other products

来源: 韩国食药处 化妆品法规信息

未列入韩国有毒物质 GHS 分类 · 现有化学物质 · 重点管理物质

来源: 韩国有毒物质 GHS 信息(环境公团)

欧盟化妆品法规 附录III(限用物质) 第96项 · 最高浓度 (a) 1.0% in fine fragrance (b) 0.4% in eau de toilette (c) 0.03% in other products · 适用 All cosmetic products, with the exception of oral products Note: 'Due to environmental concerns, musk xylene is included in the authorisation list (Annex IV) of REACH. Musk xylene cannot be placed on the market or used unless authorisation has been granted under REACH’

来源: 欧盟限用成分(附录III)

Restriction III/96 Note: 'Due to environmental concerns, musk xylene is included in the authorisation list (Annex IV) of REACH. Musk xylene cannot be placed on the market or used unless authorisation has been granted under REACH’. · Other restriction: ban substances that deplete the ozone layer

来源: 欧盟 CosIng 成分清单

详细资料——标示名称、识别编号、物性、试验记录、文献

别名和识别信息

MUSK XYLENEINCI머스크자일렌韩国标示名称(食药处标准名)Benzene, 1-(1,1-dimethylethyl)-3,5-dimethyl-2,4,6-trinitro-同义名
CAS No.化学物质登记号
81-15-2
EC No.欧盟化学品目录编号
201-329-4
DTXSID美国EPA化学品编号
DTXSID1021405
DTXCID美国EPA化合物编号
DTXCID901405
IUPAC
1-tert-Butyl-3,5-dimethyl-2,4,6-trinitrobenzene
分子式
C12H15N3O6
分子量
297.267 g/mol

实测物性

性状
5-tert-Butyl-2,4,6-trinitro-m-xylene is a white to light-colored crystalline solid. It is insoluble in water and denser than water. Hence sinks in water. Contact may irritate skin, eyes, and mucous membranes. May be toxic by ingestion. Used to make other chemicals. · Plates, needles from alcohol
气味
Strong musk odor · Sweet, musky odor
熔点
111.5 °C
溶解性
In water, 0.15 mg/L at 22 °C · In water, 0.49 mg/L at 25 °C
密度
0.77 g/cu cm
熔点/凝固点
110 ℃
蒸气压
0.000000635 ㎜Hg (at 25℃)
溶解度
0.472 ㎎/ℓ (at 25℃ (估算值))
正辛醇/水分配系数(Kow)
4.45
分子量
297.27

这是对物质本身测得的数值。韩国安全保健公团(KOSHA)的资料仅供编写和审核安全数据表参考,并非原料商品的规格。

来源: PubChem · 韩国安全保健公团 安全数据表

产品实际使用的用途

这是向美国 EPA 申报含该成分的 2 款产品的用途。其中包括化妆品以外的产品,排在前几行的即为该成分的主要用途。

  • Fragrance1
  • Deodorizer1

来源: 美国EPA CompTox

刺激与致敏试验记录

记录有皮肤试验 2 项、眼部试验 1 项。

归类为低1 项

试验结论基本一致(100%)。 这是对原料本身的试验记录,与成品中所含浓度下的刺激性不同。

查看全部 3 项试验
  • Not classified
    Skin Sensitization · Screening
  • Classification not possible
    Skin Irritation · Screening
  • Category 2B
    Eye Irritation · Screening

来源: 美国EPA CompTox

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