Cetrimide is an organic molecular entity.
- Korean limit
- 0.1%
Definition
Cetrimide is an organic molecular entity.
Source: PubChem
US FDA substance register · UNII 8483H94W1E · registered name TETRADONIUM BROMIDE · single chemical substance
Cosmetic roles
Safety & regulatory references
- Restricted
- South Korea
Source: MFDS (Korea) cosmetic regulatory information
Argentina · Brazil
- Maximum concentration permitted at final product : 0.1%
ASEAN
- Maximum authorised concentration in the finished cosmetic product : 0.1%
China
- Maximum concentration : (a) 0.25%
- (b)
European Union
- Maximum concentration in ready for use preparation : 0.1%
Source: MFDS (Korea) cosmetic regulatory information
Not classified under Korea’s toxic-substance GHS list · existing chemical substance
Restriction V/44
Source: EU CosIng ingredient list
Reviewed by CIR: Safety Assessment of Trimoniums as used in Cosmetics
More data — names, identifiers, properties, test records, literature
Official labels & definitions
JCIA labelling name ミルトリモニウムブロミド: 本品は、次の化学式で表される４級アンモニウム塩である。
Source: JCIA labelling names (Japan)
Names & identifiers
- CAS No.chemical registry number
- 1119-97-7
- EC No.EU chemical inventory number
- 214-291-9
- DTXSIDUS EPA chemical ID
- DTXSID0044367
- DTXCIDUS EPA compound ID
- DTXCID8024367
- IUPAC
- N,N,N-Trimethyltetradecan-1-aminium bromide
- Molecular formula
- C17H38BrN
- Molecular weight
- 336.402 g/mol
Measured properties
- Appearance
- White solid, [Merck Index] Colorless hygroscopic crystals, [Sigma-Aldrich MSDS] · solid
- Colour
- white
- Melting/freezing point
- 245~250 ℃
- Flash point
- &, gt, 93.3 ℃
- Water solubility
- (20%)
- Molecular weight
- 336.41
Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.
Source: PubChem · KOSHA safety data sheets (Korea)
What products actually use it for
What the 4 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Preservative2
- Anti-static agent1
- Biocide1
Source: US EPA CompTox dashboard
Irritation and sensitisation studies
3 skin studies and 4 eye studies are on record.
The studies disagree (the most common conclusion covers 33%), so they do not establish that this ingredient is irritating. These tests are on the raw material itself; irritation at the amount in a finished product is a different question.
See all 7 studies
- Category 8.2C (Category 1C)
Skin Irritation · Read Across - Severe Irritation
skin irritation: in vivo · Screening · other guideline: Appraisal of the Safety of Chemicals in Foods, Drugs, and Cosmetics according to - Not likely to be sensitizing
skin sensitisation: in vivo (non-LLNA) · Screening · according to OECD Guideline 406 (Skin Sensitisation) - Corrosive or Irritation Persists for > 21 days
eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) according to - Severe Irritation
eye irritation: in vivo · Screening · other guideline: Federal Register , April 1974 according to - Severe Irritation
eye irritation: in vivo · Screening · other guideline: Federal Register, April 1974 according to - Category 8.3A (Category 1)
Eye Irritation · Read Across
Source: US EPA CompTox dashboard
Linked databases 18
- Australian Industrial Chemicals Inventory (AICIS)
- China inventory of existing ingredients (IECIC)
- EU CosIng ingredient list 2
- JCIA labelling names (Japan)
- Korea Cosmetic Association ingredient dictionary
- Korea toxic substances GHS register (NIER)
- KOSHA safety data sheets (Korea)
- MFDS (Korea) cosmetic ingredient register 2
- MFDS (Korea) cosmetic regulatory information 2 3
- NIST Chemistry WebBook
- PubChem 2
- UniChem cross-reference IDs
- US Cosmetic Ingredient Review (CIR) 2
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata