(+)-neomenthol is a p-menthan-3-ol.
定义
(+)-neomenthol is a p-menthan-3-ol.
来源: PubChem
美国FDA 物质登记 · UNII 89S3KO7RR9 · 登记名称 Neomenthol, (±)- · 单一化学物质
化妆品中的作用
为产品增添香味PERFUMING
详细资料——标示名称、识别编号、物性、试验记录、文献
别名和识别信息
NEOMENTHOLINCICyclohexanol, 5-methyl-2-(1-methylethyl)-, (1R,2R,5S)-rel-同义名
- CAS No.化学物质登记号
- 3623-51-6
- EC No.欧盟化学品目录编号
- 222-824-1
- DTXSID美国EPA化学品编号
- DTXSID20883998
- DTXCID美国EPA化合物编号
- DTXCID001325320
- IUPAC
- (1S,2S,5R)-5-Methyl-2-(propan-2-yl)cyclohexan-1-ol
- 分子式
- C10H20O
- 分子量
- 156.269 g/mol
实测物性
- 性状
- D,l-menthol is a white crystalline solid with a peppermint odor and taste. (NTP, 1992) · Other Solid, Liquid
- 沸点
- 421 °F at 760 mmHg (NTP, 1992) · 95.00 °C. @ 12.00 mm Hg
- 熔点
- 100 °F (NTP, 1992) · -22 °C
- 溶解性
- less than 1 mg/mL at 70 °F (NTP, 1992) · very soluble in alcohol and volatile oils, slightly soluble in water
- 密度
- 0.904 at 59 °F (NTP, 1992) - Less dense than water, will float · 0.901 (20 °C), 0.891 (30 °C)
这是对物质本身测得的数值，并非原料商品的规格。
来源: PubChem
产品实际使用的用途
刺激与致敏试验记录
记录有皮肤试验 3 项、眼部试验 4 项。
归类为刺激性高2 项归类为低2 项
各项试验结论不一（最多的结论占 50%），因此不能断定该成分有刺激性。 这是对原料本身的试验记录，与成品中所含浓度下的刺激性不同。
查看全部 7 项试验
- Not likely to be sensitizing
skin sensitisation: in vivo (LLNA) · Screening · according to OECD Guideline 429 (Skin Sensitisation: Local Lymph Node Assay) other: Kimber, I, Hilton, J., Weisenberger, C., The murine local lymph node assay for identification of contact allergens: A preliminary evaluation of in situ measurement of lymphocyte proliferation. Contact Dermatitis, 21, 215- 220, 19 according to EU Method B.42 (Skin Sensitisation: Local Lymph Node Assay) - Not likely to be sensitizing
skin sensitisation: in vivo (non-LLNA) · Screening · according to OECD Guideline 406 (Skin Sensitisation) - Severe Irritation
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) 1981's version according to - Studies Indicate No Significant Irritation
eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) according to - Ambiguous
eye irritation: in vitro / ex vivo · Screening · OECD Guideline 437 (Bovine Corneal Opacity and Permeability Test Method for Identifying Ocular Corrosives and Severe Irritants) [before 26 July 2013] according to - Studies Indicate No Significant Irritation
eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) 1989 according to - Severe Irritation
eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) according to
来源: 美国EPA CompTox
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