Neotame is a dipeptide composed of N-(3,3-dimethylbutyl)-L-aspartic acid and methyl L-phenylalanate units joined by a peptide linkage.
Definition
US FDA substance register · UNII VJ597D52EX · registered name NEOTAME · single chemical substance
Neotame is a dipeptide composed of N-(3,3-dimethylbutyl)-L-aspartic acid and methyl L-phenylalanate units joined by a peptide linkage. It has a role as a xenobiotic, a sweetening agent and an environmental contaminant.
Source: PubChem
Neotame is the organic compound that conforms to the formula:
Cosmetic roles
More data — names, identifiers, properties, test records, literature
Official labels & definitions
JCIA labelling name ネオテーム: 本品は、次の化学式で表される有機化合物である。
Source: JCIA labelling names (Japan)
Names & identifiers
- CAS No.chemical registry number
- 165450-17-9
- EC No.EU chemical inventory number
- 605-408-8
- DTXSIDUS EPA chemical ID
- DTXSID50167950
- DTXCIDUS EPA compound ID
- DTXCID2090441
- IUPAC
- Methyl N-(3,3-dimethylbutyl)-L-alpha-aspartyl-L-phenylalaninate
- Molecular formula
- C20H30N2O5
- Molecular weight
- 378.469 g/mol
Measured properties
- Appearance
- white to off-white powder
- Melting point
- 81 °C to 84 °C
- Solubility
- 4,75 % (w/w) at 60 °C in water, soluble in ethanol and ethyl acetate
- Stability
- The degradation of neotame was assessed at an artificially high concentration of 200 ppm in mock beverages containing phosphate- and citrate-buffered solutions simulating formulations used in commercial cola soft drinks (pH 2.8 and 3.2) lemon-lime soft drink (pH 3.8) and root beer soft drink (pH 4.5), and covered a range of temperatures (5, 20, 30, and 35 °C) and storage for up to 8 weeks. These c
- pH
- 5,0-7,0 (0,5 % aqueous solution)
- Dissociation constant
- pKa1 = 4.11, pKa2 = 7.70, pKa3 = 6.45
Values measured on the substance itself, not a specification for a commercial raw material.
Source: PubChem
What products actually use it for
What the 5 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Flavouring and nutrient3
- Deodorizer2
Source: US EPA CompTox dashboard
Related literature
Linked databases 15
- ChEBI
- ChEMBL
- EU CosIng ingredient list 2
- JCIA labelling names (Japan)
- Korea Cosmetic Association ingredient dictionary
- MFDS (Korea) cosmetic ingredient register 2
- PubChem 2
- Tlooto literature search
- UniChem cross-reference IDs
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata
- Wikipedia · English · Japanese · Chinese