Nicotinyl Alcohol HF is the organic compound.
Definition
US FDA substance register · UNII 67656KJH8M · registered name NICOTINYL ALCOHOL HYDROFLUORIDE · single chemical substance
Nicotinyl Alcohol HF is the organic compound.
Cosmetic roles
Safety & regulatory references
- Restricted
- Taiwan · United Kingdom
Source: ASEAN Cosmetic Directive · EU Cosmetics Regulation · MFDS (Korea) cosmetic regulatory information · Taiwan FDA cosmetic ingredients · Taiwan FDA cosmetic regulations · UK cosmetics regulations (OPSS)
ASEAN
- Field of application and/or use : Oral hygiene products
- Maximum authorised concentration in the finished cosmetic product : 0.15% calculated as F. When mixed with other fluorine compounds permitted under this Annex, total F concentration must not exceed 0.15%
- Other limitations and requirements : Thailand only 0.11% calculated as F when mixed with other fluorine compounds permitted under this Annex, total F concentration must not exceed 0.11%.
- Conditions of use and warning which must be printed on the labels : • Contains nicomethanol hydrofluoride • Children of 6 years and under: Use a pea sized amount for supervised brushing to minimize swallowing. In case of intake of fluoride from other sources consult a dentist or doctor12
European Union
- Product Type, body parts : Oral products
- Maximum concentration in ready for use preparation : 0,15 % calculated as F. When mixed with other fluorine compounds permitted under this Annex, total F concentration must not exceed 0,15 %
- Wording of conditions of use and warnings : Contains nicomethanol hydrofluoride For any toothpaste with compounds containing fluorine in a concentration of 0.1 to 0.1'5.0% calculated as F unless it is already labelled as contra-indicated for children (e.g. "for adult use only") the following labelling is obligatory: "Children of 6 years and younger: use a pea-sized amount for supervised brushing to minimise swallowing. In case of intake of fluoride from other sources consult a dentist or doctor."
Source: MFDS (Korea) cosmetic regulatory information
EU Cosmetics Regulation, Annex III (restricted substances), entry 47 · maximum concentration 0,15 % calculated as F. When mixed with other fluorine compounds permitted under this Annex, total F concentration must not exceed 0,15 % · applies to Oral products
More data — names, identifiers, properties, test records, literature
Names & identifiers
- CAS No.chemical registry number
- 62756-44-9
- EC No.EU chemical inventory number
- 700-352-1
- EC No.EU chemical inventory number
- 700-352-1 (L)
- DTXSIDUS EPA chemical ID
- DTXSID201021265
- DTXCIDUS EPA compound ID
- DTXCID901506319
- IUPAC
- (Pyridin-3-yl)methanol--hydrogen fluoride (1/1)
- Molecular formula
- C6H8FNO
- Molecular weight
- 129.134 g/mol
What products actually use it for
What the 1 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Pharmaceutical (EPA)1
Source: US EPA CompTox dashboard
Irritation and sensitisation studies
1 skin studies and 0 eye studies are on record.
The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.
See all 1 studies
- High Frequency of Sensitization
skin sensitisation: in vivo (LLNA) · Screening · according to OECD Guideline 429 (Skin Sensitisation: Local Lymph Node Assay)
Source: US EPA CompTox dashboard
Linked databases 14
- ASEAN Cosmetic Directive
- EU CosIng ingredient list 2
- EU Cosmetics Regulation
- EU restricted substances (Annex III)
- MFDS (Korea) cosmetic regulatory information 2 3
- Taiwan FDA cosmetic ingredients
- Taiwan FDA cosmetic regulations
- UK cosmetics regulations (OPSS)
- UniChem cross-reference IDs
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata