Ingredient Dictionary

NINHYDRIN

Ninhydrin is a member of the class of indanones that is indane-1,3-dione bearing two additional hydroxy substituents at position 2.

Definition

Ninhydrin is a member of the class of indanones that is indane-1,3-dione bearing two additional hydroxy substituents at position 2. It has a role as a colour indicator and a human metabolite. It is a member of indanones, a ketone hydrate, a beta-diketone and an aromatic ketone.

Source: PubChem

US FDA substance register · UNII HCL6S9K23A · registered name NINHYDRIN · single chemical substance

Source: US FDA Unique Ingredient Identifier (UNII)

Cosmetic roles

Reduces other ingredientsREDUCING

Safety & regulatory references

Not classified under Korea’s toxic-substance GHS list · existing chemical substance

Source: Korea toxic substances GHS register (NIER)

Other restriction: ban substances that deplete the ozone layer

Source: EU CosIng ingredient list

More data — names, identifiers, properties, test records, literature

Names & identifiers

NINHYDRININCI닌하이드린Korean label name (MFDS standard)1H-Indene-1,3(2H)-dione, 2,2-dihydroxy-Synonym

CAS No.chemical registry number: 485-47-2
EC No.EU chemical inventory number: 207-618-1
DTXSIDUS EPA chemical ID: DTXSID7025716
DTXCIDUS EPA compound ID: DTXCID605716

IUPAC: 2,2-Dihydroxy-1H-indene-1,3(2H)-dione
Molecular formula: C9H6O4
Molecular weight: 178.143 g/mol

Measured properties

Appearance: solid
Melting/freezing point: 242 ℃
Initial boiling point and range: 351 ℃
Vapour pressure: (0.000000236mmHg)
Vapour density: 6.16
Relative density: 0.862 (at 20℃)
n-Octanol/water partition coefficient (Kow): 0.67
Decomposition temperature: 241 ℃
Molecular weight: 178.05

Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.

Source: KOSHA safety data sheets (Korea)

What products actually use it for

What the 1 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.

Reducing agent1

Source: US EPA CompTox dashboard

Irritation and sensitisation studies

1 skin studies and 1 eye studies are on record.

Classed as moderate1

The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.

See all 2 studies

Category 6.3A (Category 2)
Skin Irritation · Read Across
Category 6.4A (Category 2A)
Eye Irritation · Read Across