Definition
Nisin is a polypeptide produced by the fermentation of Lactococcus lactis
US FDA substance register · UNII EN8XKG133D · registered name NISIN · protein
Cosmetic roles
Inhibits microbial growthANTIMICROBIAL
Safety & regulatory references
Other restriction: ban substances that deplete the ozone layer
Source: EU CosIng ingredient list
More data — names, identifiers, properties, test records, literature
Names & identifiers
NISININCI니신Korean label name (MFDS standard)
- CAS No.chemical registry number
- 1414-45-5
- EC No.EU chemical inventory number
- 215-807-5
- DTXSIDUS EPA chemical ID
- DTXSID20893678
- DTXCIDUS EPA compound ID
- DTXCID301508886
- IUPAC
- N-{(1S,4S,7S,8S,11R,14S,17R,20S)-7-[(N~2~-{(3R,9S,12S,15S,21S,22S)-21-[(N~2~-{(6R,9S,10S,15aS)-10-[(3R,6S,12S,15S)-12-[(2S)-Butan-2-yl]-15-[(2Z)-2-(L-isoleucylamino)but-2-enamido]-9-methylidene-6-(2-m ethylpropyl)-5,8,11,14-tetraoxo-1-thia-4,7,10,13-tetraazacyclohexadecane-3-carboxamido]-9-methyl-1,4,11-trioxododecahydro-1H,9H-pyrrolo[2,1-i][1,4,7,10]thiatriazacyclotridecine-6-carbonyl}-L-lysyl)ami no]-15,22-dimethyl-12-(2-methylpropyl)-9-[2-(methylsulfanyl)ethyl]-5,8,11,14,17,20-hexaoxo-1-thia-4,7,10,13,16,19-hexaazacyclodocosane-3-carbonyl}-L-asparaginyl-L-methionyl-L-lysyl)amino]-14-[(1H-imid azol-5-yl)methyl]-4,8,20-trimethyl-3,6,12,15,21-pentaoxo-9,19-dithia-2,5,13,16,22-pentaazabicyclo[9.9.2]docosane-17-carbonyl}-L-seryl-L-isoleucyl-L-histidyl-N-(3-{[(1S)-5-amino-1-carboxypentyl]amino}- 3-oxoprop-1-en-2-yl)-L-valinamide
- Molecular formula
- C143H230N42O37S7
- Molecular weight
- 3354.09 g/mol
Measured properties
- Appearance
- solid
- Initial boiling point and range
- 2967 ℃
- Flash point
- 1748.039 ℃
- Vapour density
- 115.7773558853987
- Molecular weight
- 3354.07
Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.
Source: KOSHA safety data sheets (Korea)
What products actually use it for
What the 1 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Biocide1
Source: US EPA CompTox dashboard
Related literature
- Nisin J, a Novel Natural Nisin Variant, Is Produced by Staphylococcus capitis Sourced from the Human Skin Microbiota · 2019
- Impact of tannic acid on nisin encapsulation in chitosan particles. · 2023
- Nisin variants: what makes them different and unique? · 2024
- The prospect of using nisin for pre-milking treatment of the udder of cows · 2023
- Polyphasic Validation of a Nisin-Biogel to Control Canine Periodontal Disease · 2020
Linked databases 15
- Australian Industrial Chemicals Inventory (AICIS)
- ChEBI
- China inventory of existing ingredients (IECIC)
- EU CosIng ingredient list 2
- Korea Cosmetic Association ingredient dictionary
- KOSHA safety data sheets (Korea)
- MFDS (Korea) cosmetic ingredient register 2
- Tlooto literature search 2 3 4 5
- UniChem cross-reference IDs
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata
- Wikipedia · English · Japanese