Nitric acid is a nitrogen oxoacid of formula HNO3 in which the nitrogen atom is bonded to a hydroxy group and by equivalent bonds to the remaining two oxygen atoms.
Definition
Nitric acid is a nitrogen oxoacid of formula HNO3 in which the nitrogen atom is bonded to a hydroxy group and by equivalent bonds to the remaining two oxygen atoms. It has a role as a reagent and a protic solvent. It is a conjugate acid of a nitrate.
Source: PubChem
US FDA substance register · UNII 411VRN1TV4 · registered name Nitric acid · single chemical substance
Nitric Acid is the inorganic acid that conforms to the formula:
Cosmetic roles
Safety & regulatory references
Korea’s toxic-substance GHS classification: Danger · H314 (category 1) · H330 (category 1) · H271 (category 1) · +1 more
More data — names, identifiers, properties, test records, literature
Names & identifiers
- CAS No.chemical registry number
- 7697-37-2
- DTXSIDUS EPA chemical ID
- DTXSID5029685
- DTXCIDUS EPA compound ID
- DTXCID509685
- IUPAC
- Nitric acid
- Molecular formula
- HNO3
- Molecular weight
- 63.012 g/mol
Measured properties
- Appearance
- Nitric acid, other than red fuming appears as a pale yellow to reddish brown liquid with reddish brown vapors and a suffocating odor. Very toxic by inhalation. Corrosive to metals or tissue. Accelerates the burning of combustible material and may cause ignition of combustible materials upon contact. Prolonged exposure to low concentrations or short term exposure to high concentrations may result i · Nitric acid, red fuming appears as a pale yellow to reddish brown liquid generating red-brown fumes and having a suffocating odor. Very toxic by inhalation. Corrosive to metals or tissue. Prolonged exposure to low concentrations or short term exposure to high concentrations may result in adverse health effects. Rate of onset: Immediate Persistence: Hours - days Odor threshold: ~1 ppm Source/u
- Odour
- Characteristic choking odor · Acrid, Sweet to acrid
- Boiling point
- 181 °F at 760 mmHg (NIOSH, 2024) · 83 °C
- Melting point
- -44 °F (NIOSH, 2024) · -41.6 °C
- Solubility
- Miscible (NIOSH, 2024) · Very soluble in water
- Density
- 1.5 at 77 °F (NIOSH, 2024) - Denser than water, will sink · 1.5129 g/cu cm at 20 °C
- Melting/freezing point
- -41.6 ℃
- Initial boiling point and range
- 121 ℃
- Vapour pressure
- 0.89 ㎜Hg(20℃)
- Water solubility
- 500000 ㎎/ℓ(20 ℃)
- Vapour density
- 2.2
- Relative density
- 1.5128
- n-Octanol/water partition coefficient (Kow)
- -0.21
- Viscosity
- 0.746 cP(25℃)
- Molecular weight
- 63.0119
Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.
Source: PubChem · KOSHA safety data sheets (Korea)
What products actually use it for
What the 46 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Processing aids not otherwise specified7
- pH regulating agent4
- Intermediate4
- Soil amendments4
- Degradant/impurity (EPA)2
- Pigment2
- Catalyst2
- Cleaning agent2
16 other uses
- Ion exchange agent2
- Oxidizing agent2
- Dehydrating agent (desiccant)2
- Reducing agent1
- Dye1
- Propellants, non-motive (blowing agents)1
- Surface modifier1
- Energy releasers (explosives, motive propellant)1
- Plating agent1
- Semiconductor and photovoltaic agent1
- Solvent1
- Solids separation (precipitating) agent, not other1
- Corrosion inhibitor1
- No specific technical function1
- Preservative1
- Etching agent1
Source: US EPA CompTox dashboard
Irritation and sensitisation studies
8 skin studies and 3 eye studies are on record.
The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.
See all 11 studies
- Classification not possible
Skin Sensitization · Screening - Skin corrosion/irritation - Category 1
Skin Irritation · Screening - Category 1
Skin Irritation · Screening - Skin Corr. 1A
Skin Irritation · Screening - Skin Corr. 1A
Skin Irritation · Authoritative - Category 8.2A (Category 1A)
Skin Irritation · Read Across - Category 8.2C (Category 1C)
Skin Irritation · Read Across - Category 8.2B (Category 1B)
Skin Irritation · Read Across - Eye Dam. 1
Eye Irritation · Screening - Category 1
Eye Irritation · Screening - Category 8.3A (Category 1)
Eye Irritation · Read Across
Source: US EPA CompTox dashboard
Related literature
- Topical treatment of equine aural plaques with nitric acid and zinc solution. · 2026
- Topical Nitric Acid Burns: Initial Assessment and Management · 2023
- Case report: Mixed hydrofluoric and nitric acid mist inhalation poisoning · 2024
- Effect of Nitric Acid on Cutaneous and Plantar warts–a case report · 2016
- Nasal burn by nitric acid · 2007
Linked databases 17
- Australian Industrial Chemicals Inventory (AICIS)
- ChEBI
- EU CosIng ingredient list 2
- Korea Cosmetic Association ingredient dictionary
- Korea toxic substances GHS register (NIER)
- KOSHA safety data sheets (Korea)
- MFDS (Korea) cosmetic ingredient register 2
- NIST Chemistry WebBook
- PubChem 2
- Tlooto literature search 2 3 4 5
- UniChem cross-reference IDs
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata
- Wikipedia · Korean · English · Japanese · Chinese