Ingredient Dictionary

NITROFURAZONE

Nitrofurazone can cause cancer according to The Environmental Protection Agency (EPA).

Definition

Nitrofurazone can cause cancer according to The Environmental Protection Agency (EPA).

Source: PubChem

US FDA substance register · UNII X8XI70B5Z6 · registered name Nitrofurazone · single chemical substance

Source: US FDA Unique Ingredient Identifier (UNII)

Cosmetic roles

Inhibits microbial growthANTIMICROBIAL

More data — names, identifiers, properties, test records, literature

Names & identifiers

NITROFURAZONEINCIHydrazinecarboxamide, 2-[(5-nitro-2-furanyl)methylene]-Synonym

CAS No.chemical registry number: 59-87-0
EC No.EU chemical inventory number: 200-443-1
DTXSIDUS EPA chemical ID: DTXSID5020944
DTXCIDUS EPA compound ID: DTXCID30809629

IUPAC: 2-[(5-Nitrofuran-2-yl)methylidene]hydrazine-1-carboxamide
Molecular formula: C6H6N4O4
Molecular weight: 198.138 g/mol

Measured properties

Appearance: Nitrofurazone appears as odorless pale yellow needles or yellow powder. pH (saturated aqueous solution) 6.0 - 6.5. Alkaline solutions are dark orange. (NTP, 1992) · Odorless, lemon-yellow crystalline powder, [HSDB]
Odour: ODORLESS · odourless
Boiling point: 236-240 °C
Melting point: 457 to 464 °F (decomposes) (NTP, 1992) · 238 dec °C
Solubility: less than 1 mg/mL at 66 °F (NTP, 1992) · 210 mg/L (at 25 °C)
Stability: DARKENS ON PROLONGED EXPOSURE TO LIGHT · SENSITIVE TO HEAT
pH: 6.0-6.5 (SATURATED WATER SOLN) · 6.0-6.5 ()
Dissociation constant: 10
Initial boiling point and range: 236 ℃
Water solubility: 0.000238 g/㎖
Molecular weight: 198.14

Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.

Source: PubChem · KOSHA safety data sheets (Korea)

What products actually use it for

What the 1 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.

Biocide1

Source: US EPA CompTox dashboard

Irritation and sensitisation studies

2 skin studies and 0 eye studies are on record.

Classed as moderate1

The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.

See all 2 studies

SkinSens1
Skin Sensitization · QSAR Predicted
Category 6.5B (Category 1)
Skin Sensitization · Read Across