Nitromethane can cause cancer according to The National Toxicology Program.
Definition
Nitromethane can cause cancer according to The National Toxicology Program.
Source: PubChem
US FDA substance register · UNII RU5WG8C3F4 · registered name NITROMETHANE · single chemical substance
Cosmetic roles
Safety & regulatory references
- Restricted or banned
- China · South Korea
- Restricted
- United Kingdom
Source: MFDS (Korea) cosmetic regulatory information · ASEAN Cosmetic Directive · EU Cosmetics Regulation · UK cosmetics regulations (OPSS)
Argentina · Brazil
- Field of application and/or use : Corrosion inhibitor
- Maximum concentration permitted at final product : 0.3%
ASEAN
- Field of application and/or use : Rust inhibitor
- Maximum authorised concentration in the finished cosmetic product : 0.3%
European Union
- Product Type, body parts : Rust inhibitor
- Maximum concentration in ready for use preparation : 0.3%
Source: MFDS (Korea) cosmetic regulatory information
Korea’s toxic-substance GHS classification: Warning · H226 (category 3) · H351 (category 2) · H412 (category 3) · +1 more
EU Cosmetics Regulation, Annex III (restricted substances), entry 18 · maximum concentration 0.3% · applies to Rust inhibitor
Restriction III/18 · Other restriction: ban substances that deplete the ozone layer
Source: EU CosIng ingredient list
More data — names, identifiers, properties, test records, literature
Names & identifiers
- CAS No.chemical registry number
- 75-52-5
- EC No.EU chemical inventory number
- 200-876-6
- DTXSIDUS EPA chemical ID
- DTXSID2020977
- DTXCIDUS EPA compound ID
- DTXCID40977
- IUPAC
- Nitromethane
- Molecular formula
- CH3NO2
- Molecular weight
- 61.04 g/mol
Measured properties
- Appearance
- liquid
- Colour
- colourless
- pH
- 6.12
- Melting/freezing point
- -29 ℃
- Initial boiling point and range
- 101 ℃
- Flash point
- 35 ℃
- Upper/lower flammability or explosive limits
- 63 / 7.3 %
- Vapour pressure
- 35.8 ㎜Hg(20℃)
- Water solubility
- 11.1 g/100㎖(25 ℃)
- Vapour density
- 2.1
- Relative density
- 1.14
- n-Octanol/water partition coefficient (Kow)
- -0.35
- Auto-ignition temperature
- 417 ℃
- Decomposition temperature
- -709 ℃(kJ/mo)
- Viscosity
- 0.647 cP(25℃)
- Molecular weight
- 61.0397
Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.
Source: KOSHA safety data sheets (Korea)
What products actually use it for
What the 5 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Fuel2
- Intermediate2
- Corrosion inhibitor1
Source: US EPA CompTox dashboard
Irritation and sensitisation studies
4 skin studies and 2 eye studies are on record.
The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.
See all 6 studies
- Classification not possible
Skin Sensitization · Screening - Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) equivalent or similar to - Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · other guideline: Draize test according to - Not classified
Skin Irritation · Screening - Category 2
Eye Irritation · Screening - Moderate or Mild Irritation
eye irritation: in vivo · Screening · other guideline: United States Federal Hazardous Substances Act Regulations (16CFR 1500.42) according to
Source: US EPA CompTox dashboard
Related literature
- Nitromethane. · 2020
- Accidental Adhesion of Both Hands with Super Glue: A Case Report · 2016
- Responsive Polyelectrolyte Gel Membranes · 2006
- False elevation of serum creatinine following skin absorption of nitromethane complicates the clinical diagnosis of rhabdomyolysis. · 1998
- PHOTOCHEMICAL SENSITIZATION BY AZATHIOPRINE AND ITS METABOLITES. PART 3. A DIRECT EPR AND SPIN‐TRAPPING STUDY OF LIGHT‐INDUCED FREE RADICALS FROM 6‐MERCAPTOPURINE AND ITS OXIDATION PRODUCTS · 1994
Linked databases 23
- ASEAN Cosmetic Directive
- Australian Industrial Chemicals Inventory (AICIS)
- ChEBI
- ChEMBL
- EU CosIng ingredient list 2
- EU Cosmetics Regulation
- EU restricted substances (Annex III)
- IARC carcinogen classification
- Korea toxic substances GHS register (NIER)
- KOSHA safety data sheets (Korea)
- MFDS (Korea) cosmetic regulatory information 2 3 4
- NIST Chemistry WebBook
- PubChem
- Tlooto literature search 2 3 4 5
- UK cosmetics regulations (OPSS)
- UniChem cross-reference IDs
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- US National Toxicology Program reports 2 3
- Wikidata
- Wikipedia · Korean · English · Japanese · Chinese