Nobiletin is a methoxyflavone that is flavone substituted by methoxy groups at positions 5, 6, 7, 8, 3' and 4' respectively.
定义
Nobiletin is a methoxyflavone that is flavone substituted by methoxy groups at positions 5, 6, 7, 8, 3' and 4' respectively. It has a role as an antineoplastic agent and a plant metabolite. It is functionally related to a flavone.
来源: PubChem
美国FDA 物质登记 · UNII D65ILJ7WLY · 登记名称 NOBILETIN · 单一化学物质
Nobiletin is the organic compound that conforms to the formula.
化妆品中的作用
延缓产品因氧化变质ANTIOXIDANT抑制微生物生长ANTIMICROBIAL防止产品中微生物滋生PRESERVATIVE
详细资料——标示名称、识别编号、物性、试验记录、文献
别名和识别信息
NOBILETININCI노빌레틴韩国标示名称（食药处标准名）
- CAS No.化学物质登记号
- 478-01-3
- DTXSID美国EPA化学品编号
- DTXSID30197275
- DTXCID美国EPA化合物编号
- DTXCID40119766
- IUPAC
- 2-(3,4-Dimethoxyphenyl)-5,6,7,8-tetramethoxy-4H-1-benzopyran-4-one
- 分子式
- C21H22O8
- 分子量
- 402.399 g/mol
实测物性
- 性状
- Solid · 气体
- 熔点
- 134 °C
- 熔点/凝固点
- -133.89 ℃(估算值)
- 分子量
- 44.10 (估算值)
这是对物质本身测得的数值。韩国安全保健公团（KOSHA）的资料仅供编写和审核安全数据表参考，并非原料商品的规格。
来源: PubChem · 韩国安全保健公团 安全数据表
产品实际使用的用途
这是向美国 EPA 申报含该成分的 3 款产品的用途。其中包括化妆品以外的产品，排在前几行的即为该成分的主要用途。
- Preservative1
- Biocide1
- Antioxidant1
来源: 美国EPA CompTox
相关文献
- Nobiletin Induces Ferroptosis in Human Skin Melanoma Cells Through the GSK3β-Mediated Keap1/Nrf2/HO-1 Signalling Pathway · 2022
- Nobiletin mitigates benign prostatic hyperplasia by suppressing prostate cell proliferation through regulation of cell cycle progression, signaling pathways, transcription factor activity, and the androgen-signaling axis · 2025
- Nobiletin Decreases Inflammatory Mediator Expression in Tumor Necrosis Factor-Stimulated Human Periodontal Ligament Cells · 2021
- Antioxidant Nobiletin Enhances Oocyte Maturation and Subsequent Embryo Development and Quality · 2020
- 175 Nobiletin enhances the quality of in vitro-matured bovine oocytes and blastocysts by altering the transcription of key developmental genes · 2019