(+)-nootkatone is a sesquiterpenoid that is 4,4a,5,6,7,8-hexahydronaphthalen-2(3H)-one which is substituted by methyl groups at positions 4 and 4a, and by an isopropenyl group at position 6 (the 4R,4aS,6R stereoisomer).
定義
(+)-nootkatone is a sesquiterpenoid that is 4,4a,5,6,7,8-hexahydronaphthalen-2(3H)-one which is substituted by methyl groups at positions 4 and 4a, and by an isopropenyl group at position 6 (the 4R,4aS,6R stereoisomer). It has a role as a fragrance, an insect repellent and a plant metabolite. It is a sesquiterpenoid, a carbobicyclic compound and an enone.
出典: PubChem
米国FDA 物質登録 · UNII IZ2Y119N4J · 登録名 NOOTKATONE · 単一の化学物質
Nootkatone is the organic compound that conforms to the formula
化粧品での役割
安全性・規制情報
- 制限
- 国際香料基準（IFRA）
出典: IFRA 香料基準
詳しい資料 — 表示名・識別番号・物性・試験記録・文献
別名・識別情報
- CAS No.化学物質登録番号
- 4674-50-4
- EC No.EU化学物質目録番号
- 225-124-4
- DTXSID米国EPA化学物質番号
- DTXSID8047050
- DTXCID米国EPA化合物番号
- DTXCID6027050
- IUPAC
- (4R,4aS,6R)-4,4a-Dimethyl-6-(prop-1-en-2-yl)-4,4a,5,6,7,8-hexahydronaphthalen-2(3H)-one
- 分子式
- C15H22O
- 分子量
- 218.34 g/mol
製品が実際に使っている用途
米国EPAにこの成分を届け出た製品5件の用途です。化粧品以外の製品も含まれるため、上の数行がこの成分の主な使い道といえます。
- Fragrance3
- Flavouring and nutrient2
出典: 米国EPA CompTox
関連文献
- Nootkatone (NK), a grapefruit-derived sesquiterpenoid, suppresses UVB-induced damage by regulating NRF2-HO-1 and AhR-CYP1A1 signaling pathways in HaCaT cells · 2024
- Valorization of hydro-distillate of fruit peels of Citrus paradisi macfad. Cultivar. Foster: Chemical profiling, antioxidant evaluation and in vitro and in silico enzyme inhibition studies · 2024
- Production, Function, and Applications of the Sesquiterpenes Valencene and Nootkatone: a Comprehensive Review. · 2022
- Differential proteomic analysis of citrus flavor (+)-valencene biotransformation to (+)-nootkatone by Yarrowia lipolytica. · 2022
- Advances on (+)-nootkatone microbial biosynthesis and its related enzymes · 2021