(+)-nootkatone is a sesquiterpenoid that is 4,4a,5,6,7,8-hexahydronaphthalen-2(3H)-one which is substituted by methyl groups at positions 4 and 4a, and by an isopropenyl group at position 6 (the 4R,4aS,6R stereoisomer).
定义
(+)-nootkatone is a sesquiterpenoid that is 4,4a,5,6,7,8-hexahydronaphthalen-2(3H)-one which is substituted by methyl groups at positions 4 and 4a, and by an isopropenyl group at position 6 (the 4R,4aS,6R stereoisomer). It has a role as a fragrance, an insect repellent and a plant metabolite. It is a sesquiterpenoid, a carbobicyclic compound and an enone.
来源: PubChem
美国FDA 物质登记 · UNII IZ2Y119N4J · 登记名称 NOOTKATONE · 单一化学物质
Nootkatone is the organic compound that conforms to the formula
化妆品中的作用
安全与法规参考
- 限用
- 国际香料标准（IFRA）
来源: IFRA 香料标准
详细资料——标示名称、识别编号、物性、试验记录、文献
别名和识别信息
- CAS No.化学物质登记号
- 4674-50-4
- EC No.欧盟化学品目录编号
- 225-124-4
- DTXSID美国EPA化学品编号
- DTXSID8047050
- DTXCID美国EPA化合物编号
- DTXCID6027050
- IUPAC
- (4R,4aS,6R)-4,4a-Dimethyl-6-(prop-1-en-2-yl)-4,4a,5,6,7,8-hexahydronaphthalen-2(3H)-one
- 分子式
- C15H22O
- 分子量
- 218.34 g/mol
产品实际使用的用途
这是向美国 EPA 申报含该成分的 5 款产品的用途。其中包括化妆品以外的产品，排在前几行的即为该成分的主要用途。
- Fragrance3
- Flavouring and nutrient2
来源: 美国EPA CompTox
相关文献
- Nootkatone (NK), a grapefruit-derived sesquiterpenoid, suppresses UVB-induced damage by regulating NRF2-HO-1 and AhR-CYP1A1 signaling pathways in HaCaT cells · 2024
- Valorization of hydro-distillate of fruit peels of Citrus paradisi macfad. Cultivar. Foster: Chemical profiling, antioxidant evaluation and in vitro and in silico enzyme inhibition studies · 2024
- Production, Function, and Applications of the Sesquiterpenes Valencene and Nootkatone: a Comprehensive Review. · 2022
- Differential proteomic analysis of citrus flavor (+)-valencene biotransformation to (+)-nootkatone by Yarrowia lipolytica. · 2022
- Advances on (+)-nootkatone microbial biosynthesis and its related enzymes · 2021