Definition
US FDA substance register · UNII 79K39JU7RN · registered name OLEAMIDOPROPYL DIMETHYLAMINE · single chemical substance
Cosmetic roles
Safety & regulatory references
Korea’s toxic-substance GHS classification: Warning · H302 (category 4) · H400 (category 1)
Reviewed by CIR: Safety Assessment of Fatty Acid Amidopropyl Dimethylamines as Used in Cosmetics
More data — names, identifiers, properties, test records, literature
Names & identifiers
- CAS No.chemical registry number
- 109-28-4
- CAS No.chemical registry number
- 126150-52-5
- CAS No.chemical registry number
- 149879-92-5
- EC No.EU chemical inventory number
- 203-661-5
- DTXSIDUS EPA chemical ID
- DTXSID10873803
- DTXCIDUS EPA compound ID
- DTXCID20912232
- IUPAC
- (9Z)-N-[3-(Dimethylamino)propyl]octadec-9-enamide
- Molecular formula
- C23H46N2O
- Molecular weight
- 366.634 g/mol
Measured properties
- Appearance
- Liquid · liquid
- Melting/freezing point
- 316.93 ℃
- Initial boiling point and range
- 504.8 ℃(760 mmHg)
- Flash point
- 54 ℃
- Vapour pressure
- 3.85E-11 ㎜Hg
- Water solubility
- 1260 ㎎/ℓ
- Vapour density
- 12.655850880220918
- n-Octanol/water partition coefficient (Kow)
- 1.842
Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.
Source: PubChem · KOSHA safety data sheets (Korea)
What products actually use it for
What the 5 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Surfactant (surface active agent)2
- Anti-static agent1
- Intermediate1
- Fragrance1
Source: US EPA CompTox dashboard
Irritation and sensitisation studies
1 skin studies and 0 eye studies are on record.
The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.
See all 1 studies
- SkinIrr2
Skin Irritation · QSAR Predicted
Source: US EPA CompTox dashboard
Related literature
- Titanium allergy as a likely cause of post‐reconstruction dermatitis of the breast · 2021
- Chronic Actinic Dermatitis after Occupational Sensitization to the Epoxy Resin, Bisphenol · 2020
- CD10 Challenges with chambers: a case of contact allergy to patch test units · 2025
- Prevalence of Surfactant in the Contact Allergen Management Program · 2019
- Occupational allergic contact dermatitis from 3‐dimethylaminopropylamine in shampoos · 1996
Linked databases 16
- Australian Industrial Chemicals Inventory (AICIS)
- China inventory of existing ingredients (IECIC)
- EU CosIng ingredient list 2
- Korea Cosmetic Association ingredient dictionary
- Korea toxic substances GHS register (NIER)
- KOSHA safety data sheets (Korea)
- MFDS (Korea) cosmetic ingredient register 2
- PubChem
- Tlooto literature search 2 3 4 5
- UniChem cross-reference IDs
- US Cosmetic Ingredient Review (CIR) 2
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata