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Ingredient Dictionary

OLEOCANTHAL

Oleocanthal is a carboxylic ester that is the 2-(p-hydroxyphenyl)ethyl ester of (3S)-4-formyl-3-(2-oxoethyl)hex-4-enoic acid.

Molecular structure

Definition

US FDA substance register · UNII AC7QO6038O · registered name OLEOCANTHAL · single chemical substance

Source: US FDA Unique Ingredient Identifier (UNII)

Oleocanthal is a carboxylic ester that is the 2-(p-hydroxyphenyl)ethyl ester of (3S)-4-formyl-3-(2-oxoethyl)hex-4-enoic acid. Oleocanthal is found in olive oil but it is not clear whether the natural product is a mixture of E/Z isomers or a single isomer as the two isomers readily interconvert in solution; most pharmacological studies will have been performed using a mixture. It has a role as an antioxidant, a non-steroidal anti-inflammatory drug, an antineoplastic agent, a cyclooxygenase 2 inhibitor, a cyclooxygenase 1 inhibitor, a nutraceutical, a neuroprotective agent, a Hsp90 inhibitor, an anti-inflammatory agent, an apoptosis inducer and a plant metabolite. It is a carboxylic ester, a member of phenols, a dialdehyde and an enal. It is functionally related to a 2-(4-hydroxyphenyl)ethanol.

Source: PubChem

Oleocanthal is the organic compound that conforms to the formula:

Cosmetic roles

Cares for the mouthORAL CAREProtects skin from outside irritantsSKIN PROTECTINGSlows spoilage by oxygenANTIOXIDANTInhibits microbial growthANTIMICROBIAL
More data — names, identifiers, properties, test records, literature

Names & identifiers

OLEOCANTHALINCI
CAS No.chemical registry number
289030-99-5
DTXSIDUS EPA chemical ID
DTXSID40183104
DTXCIDUS EPA compound ID
DTXCID10105595
IUPAC
2-(4-Hydroxyphenyl)ethyl (3S,4E)-4-formyl-3-(2-oxoethyl)hex-4-enoate
Molecular formula
C17H20O5
Molecular weight
304.342 g/mol

What products actually use it for

What the 3 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.

  • Humectant1
  • Biocide1
  • Antioxidant1

Source: US EPA CompTox dashboard

Related literature

Linked databases 12