Oleocanthal is a carboxylic ester that is the 2-(p-hydroxyphenyl)ethyl ester of (3S)-4-formyl-3-(2-oxoethyl)hex-4-enoic acid.
定義
米国FDA 物質登録 · UNII AC7QO6038O · 登録名 OLEOCANTHAL · 単一の化学物質
Oleocanthal is a carboxylic ester that is the 2-(p-hydroxyphenyl)ethyl ester of (3S)-4-formyl-3-(2-oxoethyl)hex-4-enoic acid. Oleocanthal is found in olive oil but it is not clear whether the natural product is a mixture of E/Z isomers or a single isomer as the two isomers readily interconvert in solution; most pharmacological studies will have been performed using a mixture. It has a role as an antioxidant, a non-steroidal anti-inflammatory drug, an antineoplastic agent, a cyclooxygenase 2 inhibitor, a cyclooxygenase 1 inhibitor, a nutraceutical, a neuroprotective agent, a Hsp90 inhibitor, an anti-inflammatory agent, an apoptosis inducer and a plant metabolite. It is a carboxylic ester, a member of phenols, a dialdehyde and an enal. It is functionally related to a 2-(4-hydroxyphenyl)ethanol.
出典: PubChem
Oleocanthal is the organic compound that conforms to the formula:
化粧品での役割
詳しい資料 — 表示名・識別番号・物性・試験記録・文献
別名・識別情報
- CAS No.化学物質登録番号
- 289030-99-5
- DTXSID米国EPA化学物質番号
- DTXSID40183104
- DTXCID米国EPA化合物番号
- DTXCID10105595
- IUPAC
- 2-(4-Hydroxyphenyl)ethyl (3S,4E)-4-formyl-3-(2-oxoethyl)hex-4-enoate
- 分子式
- C17H20O5
- 分子量
- 304.342 g/mol
製品が実際に使っている用途
米国EPAにこの成分を届け出た製品3件の用途です。化粧品以外の製品も含まれるため、上の数行がこの成分の主な使い道といえます。
- Humectant1
- Biocide1
- Antioxidant1
出典: 米国EPA CompTox
関連文献
- Evaluating the Impact of Oleocanthal and Oleacein on Skin Aging: Results of a Randomized Clinical Study · 2024
- The Benefits of Olive Oil for Skin Health: Study on the Effect of Hydroxytyrosol, Tyrosol, and Oleocanthal on Human Fibroblasts · 2023
- Exploring the Immunotherapeutic Potential of Oleocanthal against Murine Cutaneous Leishmaniasis · 2021
- Tissue Distribution of Oleocanthal and Its Metabolites after Oral Ingestion in Rats · 2021
- Topical treatment with oleocanthal extract in reducing inflammatory reactions after photodynamic therapy: a prospective quasi-experimental pilot study. · 2019