Oleocanthal is a carboxylic ester that is the 2-(p-hydroxyphenyl)ethyl ester of (3S)-4-formyl-3-(2-oxoethyl)hex-4-enoic acid.
定义
美国FDA 物质登记 · UNII AC7QO6038O · 登记名称 OLEOCANTHAL · 单一化学物质
Oleocanthal is a carboxylic ester that is the 2-(p-hydroxyphenyl)ethyl ester of (3S)-4-formyl-3-(2-oxoethyl)hex-4-enoic acid. Oleocanthal is found in olive oil but it is not clear whether the natural product is a mixture of E/Z isomers or a single isomer as the two isomers readily interconvert in solution; most pharmacological studies will have been performed using a mixture. It has a role as an antioxidant, a non-steroidal anti-inflammatory drug, an antineoplastic agent, a cyclooxygenase 2 inhibitor, a cyclooxygenase 1 inhibitor, a nutraceutical, a neuroprotective agent, a Hsp90 inhibitor, an anti-inflammatory agent, an apoptosis inducer and a plant metabolite. It is a carboxylic ester, a member of phenols, a dialdehyde and an enal. It is functionally related to a 2-(4-hydroxyphenyl)ethanol.
来源: PubChem
Oleocanthal is the organic compound that conforms to the formula:
化妆品中的作用
详细资料——标示名称、识别编号、物性、试验记录、文献
别名和识别信息
- CAS No.化学物质登记号
- 289030-99-5
- DTXSID美国EPA化学品编号
- DTXSID40183104
- DTXCID美国EPA化合物编号
- DTXCID10105595
- IUPAC
- 2-(4-Hydroxyphenyl)ethyl (3S,4E)-4-formyl-3-(2-oxoethyl)hex-4-enoate
- 分子式
- C17H20O5
- 分子量
- 304.342 g/mol
产品实际使用的用途
这是向美国 EPA 申报含该成分的 3 款产品的用途。其中包括化妆品以外的产品,排在前几行的即为该成分的主要用途。
- Humectant1
- Biocide1
- Antioxidant1
来源: 美国EPA CompTox
相关文献
- Evaluating the Impact of Oleocanthal and Oleacein on Skin Aging: Results of a Randomized Clinical Study · 2024
- The Benefits of Olive Oil for Skin Health: Study on the Effect of Hydroxytyrosol, Tyrosol, and Oleocanthal on Human Fibroblasts · 2023
- Exploring the Immunotherapeutic Potential of Oleocanthal against Murine Cutaneous Leishmaniasis · 2021
- Tissue Distribution of Oleocanthal and Its Metabolites after Oral Ingestion in Rats · 2021
- Topical treatment with oleocanthal extract in reducing inflammatory reactions after photodynamic therapy: a prospective quasi-experimental pilot study. · 2019