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Ingredients

Ingredient Dictionary

OLEUROPEIN

Molecular structure

Definition

Oleuropein is the organic compound that conforms to the formula:

US FDA substance register · UNII 2O4553545L · registered name OLEUROPEIN · single chemical substance

Source: US FDA Unique Ingredient Identifier (UNII)

Oleuropein is a secoiridoid glycoside that is the methyl ester of 3,4-dihydro-2H-pyran-5-carboxylic acid which is substituted at positions 2, 3, and 4 by hydroxy, ethylidene, and carboxymethyl groups, respectively and in which the anomeric hydroxy group at position 2 has been converted into its beta-D-glucoside and the carboxylic acid moiety of the carboxymethyl substituent has been converted to the corresponding 3,4-dihydroxyphenethyl ester (the 2S,3E,4S stereoisomer). The most important phenolic compound present in olive cultivars. It has a role as an antioxidant, an antineoplastic agent, an antihypertensive agent, a radical scavenger, a nutraceutical, an anti-inflammatory agent, an apoptosis inducer, a NF-kappaB inhibitor and a plant metabolite. It is a beta-D-glucoside, a methyl ester, a member of pyrans, a member of catechols, a secoiridoid glycoside and a diester.

Source: PubChem

Cosmetic roles

Slows spoilage by oxygenANTIOXIDANTCurls or straightens hairHAIR WAVING OR STRAIGHTENINGHolds hair in placeHAIR FIXINGSoftens hairHAIR CONDITIONING
More data — names, identifiers, properties, test records, literature

Official labels & definitions

JCIA labelling name オレウロペイン: 本品は、次の化学式で表される有機化合物である。

Source: JCIA labelling names (Japan)

Names & identifiers

OLEUROPEININCI올레우로페인Korean label name (MFDS standard)オレウロペインJapanese labelling name
CAS No.chemical registry number
32619-42-4
EC No.EU chemical inventory number
215-129-6
DTXSIDUS EPA chemical ID
DTXSID60905103
DTXCIDUS EPA compound ID
DTXCID401334206
IUPAC
Methyl (2S,3E,4S)-4-{2-[2-(3,4-dihydroxyphenyl)ethoxy]-2-oxoethyl}-3-ethylidene-2-(beta-D-glucopyranosyloxy)-3,4-dihydro-2H-pyran-5-carboxylate
Molecular formula
C25H32O13
Molecular weight
540.518 g/mol

What products actually use it for

What the 4 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.

  • Antioxidant1
  • Hair waving or straightening (EPA)1
  • Hair fixative (EPA)1
  • Softener and conditioner1

Source: US EPA CompTox dashboard

Irritation and sensitisation studies

1 skin studies and 0 eye studies are on record.

Classed as moderate1

The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.

See all 1 studies
  • SkinIrr2
    Skin Irritation · QSAR Predicted

Source: US EPA CompTox dashboard

Related literature

Linked databases 15