Osthole is a natural product found in Peucedanum ostruthium and Angelica pubescens.
Definition
Osthole is a natural product found in Peucedanum ostruthium and Angelica pubescens. It has a role as a metabolite. It is a member of coumarins and a botanical anti-fungal agent.
Source: PubChem
US FDA substance register · UNII XH1TI1759C · registered name OSTHOL · single chemical substance
Cosmetic roles
Keeps skin in good condition (CosIng catch-all)SKIN CONDITIONING
Safety & regulatory references
Other restriction: ban substances that deplete the ozone layer
Source: EU CosIng ingredient list
More data — names, identifiers, properties, test records, literature
Names & identifiers
OSTHOLEINCI오스톨Korean label name (MFDS standard)
- CAS No.chemical registry number
- 484-12-8
- DTXSIDUS EPA chemical ID
- DTXSID20197507
- DTXCIDUS EPA compound ID
- DTXCID90119998
- IUPAC
- 7-Methoxy-8-(3-methylbut-2-en-1-yl)-2H-1-benzopyran-2-one
- Molecular formula
- C15H16O3
- Molecular weight
- 244.29 g/mol
What products actually use it for
What the 1 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Softener and conditioner1
Source: US EPA CompTox dashboard
Related literature
- Osthole ameliorates chronic pruritus in 2,4-dichloronitrobenzene-induced atopic dermatitis by inhibiting IL-31 production · 2024
- Structural mechanism of TRPV3 channel inhibition by the plant‐derived coumarin osthole · 2021
- Osthole: A Traditional Chinese Medicine for Ocular Anti-Angiogenic Therapy · 2020
- Osthole attenuates mouse atopic dermatitis by inhibiting thymic stromal lymphopoietin production from keratinocytes · 2019
- Antipruritic Effect of Natural Coumarin Osthole through Selective Inhibition of Thermosensitive TRPV3 Channel in the Skin · 2018
Linked databases 15
- ChEBI
- ChEMBL
- EU CosIng ingredient list 2
- Korea Cosmetic Association ingredient dictionary
- MFDS (Korea) cosmetic ingredient register 2
- NIST Chemistry WebBook
- PubChem
- Tlooto literature search 2 3 4 5
- UniChem cross-reference IDs
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata
- Wikipedia · English · Japanese · Chinese