Isoambrettolide is a macrolide.
定义
美国FDA 物质登记 · UNII 0DI2GU512F · 登记名称 ISOAMBRETTOLIDE · 混合物
Isoambrettolide is a macrolide.
来源: PubChem
化妆品中的作用
为产品增添香味PERFUMING
安全与法规参考
未列入韩国有毒物质 GHS 分类 · 现有化学物质
详细资料——标示名称、识别编号、物性、试验记录、文献
别名和识别信息
OXACYCLOHEPTADEC-10-EN-2-ONEINCI
- CAS No.化学物质登记号
- 28645-51-4
- EC No.欧盟化学品目录编号
- 249-120-7
- DTXSID美国EPA化学品编号
- DTXSID3051965
- DTXCID美国EPA化合物编号
- DTXCID6030528
- IUPAC
- 1-Oxacycloheptadec-10-en-2-one
- 分子式
- C16H28O2
- 分子量
- 252.398 g/mol
实测物性
- 性状
- CBI · Clear colourless or pale yellow liquid, Sweet musky fruity aroma
- 沸点
- 185.00 to 190.00 °C. @ 16.00 mm Hg · 1.5-1.6 °C (0.1 mm Hg)
- 溶解性
- Soluble in non-polar solvents, insoluble in water · Soluble (in ethanol)
- 密度
- 0.949-0.957
- 初沸点和沸程
- 399.2 ℃((760 mmHg))
- 闪点
- 168.2 ℃
- 比重
- 0.893 g/cm³
- 分子量
- 252.39
这是对物质本身测得的数值。韩国安全保健公团（KOSHA）的资料仅供编写和审核安全数据表参考，并非原料商品的规格。
来源: PubChem · 韩国安全保健公团 安全数据表
产品实际使用的用途
这是向美国 EPA 申报含该成分的 25 款产品的用途。其中包括化妆品以外的产品，排在前几行的即为该成分的主要用途。
- Fragrance21
- Flavouring and nutrient2
- Deodorizer2
来源: 美国EPA CompTox
刺激与致敏试验记录
记录有皮肤试验 5 项、眼部试验 1 项。
归类为刺激性高1 项归类为低4 项
各项试验结论不一（最多的结论占 20%），因此不能断定该成分有刺激性。 这是对原料本身的试验记录，与成品中所含浓度下的刺激性不同。
查看全部 6 项试验
- Not likely to be sensitizing
skin sensitisation: in vivo (non-LLNA) · Screening · according to other guideline: Open epicutaneous test was conducted to evaluate the skin sensitization potential of o-6-Hexadecenlactone on Guinea Pigs. - Not likely to be sensitizing
skin sensitisation: in vivo (non-LLNA) · Screening · according to other guideline: Human Repeated Insult Patch Test - Not likely to be sensitizing
skin sensitisation: in vivo (non-LLNA) · Screening · according to other guideline: Skin sensitization study was conducted to evaluate the toxic nature of the test compound Ambrettolide - High Frequency of Sensitization
skin sensitisation: in vivo (non-LLNA) · Screening · according to other guideline: Skin sensitization potential of the test compound o-6-Hexadecenlactone was studied in vivo on 178 human patients - Not likely to be sensitizing
skin sensitisation · Screening · according to other guideline: Skin sensitization potential of the test compound o-6-Hexadecenlactone was studied in vivo on humans - Studies Indicate No Significant Irritation
eye irritation: in vivo · Screening · other guideline: Eye irritation study was conducted on rabbits to evaluate the irritation potential of the test compound Oxacycloheptadec-10-ene-2-one according to
来源: 美国EPA CompTox